In the post-genomic era, the goal of personalized medicine is to determine the correlation
between genotype and phenotype. Developing high-throughput genotyping technologies …

MicroRNAs (miRNAs) are a class of noncoding small RNAs that regulate gene expression
by base pairing with target mRNAs at the 3′-terminal untranslated regions (3′-UTRs) …

MicroRNAs (miRNAs) are studied as key regulators of gene expression involved in different
diseases. Several single nucleotide polymorphisms (SNPs) in miRNA genes or target sites …

Background Gene variants within regulatory regions are thought to be major contributors of
the variation of complex traits/diseases. Genome wide association studies (GWAS), have …

Abstract Background Single nucleotide polymorphisms (SNPs) can lead to the susceptibility
and onset of diseases through their effects on gene expression at the posttranscriptional …

MicroRNAs (miRNAs) function as endogenous translational repressors of protein-coding
genes in animals by binding to target sites in the 3′ UTRs of mRNAs. Because a single …

Background MicroRNAs (miRNAs) regulate several biological processes through post-
transcriptional gene silencing. The efficiency of binding of miRNAs to target transcripts …

MicroRNAs are short, approximately 22 nucleotide noncoding RNAs binding to partially
complementary sites in the 3′ UTR of target mRNAs. This process generally results in …

MicroRNAs (miRNAs) are important regulators of eukaryotic gene expression. They have
been implicated in a broad range of biological processes, and miRNA-related genetic …

Genome Wide Association Studies (GWAS) have mapped thousands of genetic variants
associated with complex disease risk and regulating quantitative traits, thus exploiting an …