[PDF][PDF] Oxidative Imbalance in Sickle Cell Disease: Unraveling the Molecular Mechanisms

EI Obeagu - Elite Journal of Health Science, 2024 - researchgate.net
Sickle cell disease (SCD) stands as one of the most prevalent genetic disorders globally,
characterized by the abnormal hemoglobin S (HbS) leading to distorted erythrocyte …

[PDF][PDF] Oxidative Stress and Redox Signaling in the Pathophysiology of Sickle Cell Disease: A Review

EI Obeagu, GU Obeagu - academia.edu
Abstract Sickle Cell Disease (SCD) is a hereditary hemoglobinopathy characterized by the
aberrant hemoglobin S, resulting in the formation of sickle-shaped red blood cells and a …

[PDF][PDF] Oxidative Damage and Vascular Complications in Sickle Cell Anemia: A Review

EI Obeagu, GU Obeagu - Elite Journal of Haematology, 2024 - researchgate.net
Sickle cell anemia (SCA) is a hereditary hemoglobinopathy characterized by the presence of
abnormal hemoglobin S (HbS), leading to the polymerization of red blood cells and the …

[PDF][PDF] Reactive Oxygen Species and Antioxidant Defense Mechanisms in Sickle Cell Anemia: A Review

EI Obeagu, GU Obeagu - Elite Journal of Laboratory Medicine, 2024 - academia.edu
Sickle cell anemia (SCA) is a genetic hemoglobinopathy characterized by abnormal
hemoglobin S (HbS) production, leading to the formation of sickle-shaped red blood cells …

Oxidative stress in sickle cell disease and emerging roles for antioxidants in treatment strategies

Y Öztaş, İİ Boşgelmez - Pathology, 2020 - Elsevier
Sickle cell disease (SCD) is an inherited hemoglobinopathy affecting millions of people
worldwide. It occurs due to a point mutation in beta-globin chain of hemoglobin (Hb). Sickle …

Oxidative stress and sickle cell disease

DGH Da Silva, EB Junior, CR Bonini-Domingos… - 2017 - repositorio.unesp.br
Sickle cell disease (SCD) embraces a group of genetic hemolytic disorders associated with
high morbidity and mortality. SCD is characterized by a complex pathophysiology initiated …

[HTML][HTML] Impacts of oxidative stress and anti-oxidants on the development, pathogenesis, and therapy of sickle cell disease: A comprehensive review

E Pavitra, RK Acharya, VK Gupta, HK Verma… - Biomedicine & …, 2024 - Elsevier
Sickle cell disease (SCD) is the most severe monogenic hemoglobinopathy caused by a
single genetic mutation that leads to repeated polymerization and depolymerization of …

Role of oxidative stress in the pathogenesis of sickle cell disease

EN Chirico, V Pialoux - IUBMB life, 2012 - Wiley Online Library
Sickle cell disease (SCD) is a class of hemoglobinopathy in humans, which causes a
disruption of the normal activities in different systems. Although this disease begins with the …

[PDF][PDF] The Impact of Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Activation on Sickle Cell Anemia: A Review

EI Obeagu - Elite Journal of Laboratory Medicine, 2024 - academia.edu
Abstract Sickle Cell Anemia (SCA) is a hereditary blood disorder characterized by the
presence of abnormal hemoglobin, leading to chronic hemolytic anemia, vaso-occlusive …

[HTML][HTML] The red blood cell—inflammation vicious circle in sickle cell disease

E Nader, M Romana, P Connes - Frontiers in immunology, 2020 - frontiersin.org
Sickle cell disease (SCD) is a genetic disease caused by a single mutation in the β-globin
gene, leading to the production of an abnormal hemoglobin called hemoglobin S (HbS) …