Growth hormone (GH) is critical for achieving normal structural growth. In addition, GH plays
an important role in regulating metabolic function. GH acts through its GH receptor (GHR) to …

A reduction in hepatocyte growth hormone (GH)-signaling promotes non-alcoholic fatty liver
disease (NAFLD). However, debate remains as to the relative contribution of the direct …

Growth hormone (GH) and downstream insulin-like growth factor 1 (IGF1) signaling mediate
growth and metabolism. GH deficiency causes short stature or dwarfism, and excess GH …

Growth hormone (GH) and insulin-like growth factor-1 (IGF-I) are pleiotropic hormones with
important roles in lifespan. They promote growth, anabolic actions, and body maintenance …

Growth hormone (GH), a master regulator of somatic growth, also regulates carbohydrate
and lipid metabolism via complex interactions with insulin and insulin-like growth factor-1 …

A unique mouse model was developed with elevated endogenous GH (2-to 3-fold) and IGF-I
(1.2-to 1.4-fold), due to somatotrope-specific Cre-mediated inactivation of IGF-I receptor …

Growth hormone (GH) binds to its receptor (growth hormone receptor [GHR]) to exert its
pleiotropic effects on growth and metabolism. Disrupted GH/GHR actions not only fail growth …

Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are two
of the most common liver diseases associated with obesity, type 2 diabetes and metabolic …

Growth hormone has been known to be diabetogenic for almost a century and it's
diabetogenic properties fostered consideration of excessive and abnormal GH secretion as …

Context: Fasting is associated with suppressed insulin and augmented GH secretion. The
involvement of each mechanism in the regulation of fuel mobilization during fasting is …