[HTML][HTML] Increased Frequencies of the ‒174G and ‒572C IL6 Alleles in Populations of Indigenous Peoples of Siberia Compared to Russians

LE Tabikhanova, LP Osipova, TV Churkina… - Molecular Biology, 2023 - Springer
The study of immune response and inflammation gene polymorphisms in a genogeographic
context is relevant in the study of human populations. Here, in the indigenous populations of …

Allele frequency distributions of -174G/C polymorphism in regulatory region of interleukin 6 gene (IL6) in Russian and worldwide populations

SA Borinskaya, AS Gureev, AA Orlova… - Russian journal of …, 2013 - Springer
Allele and genotype frequencies of the− 174G/C polymorphism (rs1800795) in the
regulatory region of the IL6 gene, which encode anti-inflammatory cytokine interleukin 6 …

Association of the genenetic polymorphism of cytokines and their receptors with climate and geographic factors in human populations

AA Cherednichenko, EA Trifonova… - Russian journal of …, 2014 - Springer
The variability of eight polymorphic variants of the IL4, IL4R, IL10, IL13, IL12A, and IL12RB2
genes encoding key cytokines and their receptors in 57 world populations has been …

Association of single nucleotide polymorphisms in the IL‐18 gene with production of IL‐18 protein by mononuclear cells from healthy donors

KO Pavlovna, SN Sergeevna… - Mediators of …, 2008 - Wiley Online Library
IL‐18 has proinflammatory effects and participates in both innate and adaptive cellular and
humoral immunity. A number of SNPs that influence IL‐18 production are found in the gene …

Marked differences of haplotype tagging SNP distribution, linkage, and haplotype profile of IL23 receptor gene in Roma and Hungarian population samples

L Magyari, D Varszegi, P Sarlos, L Jaromi, BI Melegh… - Cytokine, 2014 - Elsevier
Polymorphisms of the interleukin-23 receptor (IL23R) gene have been found to play an
important role in the development of several autoimmune diseases. We examined five …

Association between Allelic Variants of IL2, IL2RA, and IL7R Genes and Multiple Sclerosis

YR Timasheva, OV Zaplakhova, TR Nasibullin… - Russian Journal of …, 2019 - Springer
Multiple sclerosis is a chronic progressive disease of nervous system caused by a
combination of genetic and environmental factors leading to the development of a complex …

Variability of interleukin 4 and its receptor genes in native populations of Siberia

VA Stepanov, EA Trifonova, KV Simonova… - Medical …, 2015 - medgen-journal.ru
Genetic diversity of SNP markers of Interleukin 4 alpha and Interleukin 4 receptor genes was
investigated in 4 populations of native Siberian ethnic groups (Buryat, Yakut, Ket and Khant) …

Ethnic variations of IL‐10 polymorphisms in a Sami and Norwegian population

Ø Torkildsen, E Utsi, HF Harbo… - Scandinavian …, 2005 - Wiley Online Library
Abstract Interleukin‐10 (IL‐10) production is genetically determined and influenced by
different polymorphisms in the promoter region of IL‐10. These polymorphisms may …

Allele and genotype frequencies of polymorphisms in cytokine genes in ethnic Russian individuals from Moscow, Russia

A Shadrina, E Voronina, I Zolotukhin, M Filipenko - Human Immunology, 2017 - Elsevier
Two hundred and twenty eight ethnic Russian individuals from Moscow, Russia, were
genotyped at 14 single nucleotide polymorphisms CCL2 A-2578G; VEGFA C-2578A, G …

Analysis of correlation between il 6 gene polymorphism (-174 G/C) and classic risk factors in patients with previous myocardial infarctions

AV Shevchenko, OV Golovanova… - Medical Immunology …, 2014 - mimmun.ru
We have carried out a prevalence analysis of IL6 (-174 G/C) gene promoter polymorphism
and traditional cardiovascular risk factors in male patients living in the West Siberia that …