Immunotherapy in triple negative breast cancer: beyond checkpoint inhibitors

Y Abdou, A Goudarzi, JX Yu, S Upadhaya… - NPJ Breast …, 2022 - nature.com
The development of immunotherapy agents has revolutionized the field of oncology. The
only FDA-approved immunotherapeutic approach in breast cancer consists of immune …

Immunotherapy treatment for triple negative breast cancer

ER Berger, T Park, A Saridakis, M Golshan… - Pharmaceuticals, 2021 - mdpi.com
Triple-negative breast cancer (TNBC) is considered one of the highest-risk subtypes of
breast cancer and has dismal prognosis. Local recurrence rate after standard therapy in the …

Immunotherapy for triple-negative breast cancer: combination strategies to improve outcome

L Li, F Zhang, Z Liu, Z Fan - Cancers, 2023 - mdpi.com
Simple Summary For decades, countless efforts have been devoted to developing targeted
drugs to improve the prognosis of triple-negative breast cancer (TNBC). Among the novel …

Progress and prospect of immunotherapy for triple-negative breast cancer

C Luo, P Wang, S He, J Zhu, Y Shi, J Wang - Frontiers in Oncology, 2022 - frontiersin.org
Breast cancer is the most commonly diagnosed cancer (estimated 2.3 million new cases in
2020) and the leading cause of cancer death (estimated 685,000 deaths in 2020) in women …

Immunotherapeutic interventions of triple negative breast cancer

Z Li, Y Qiu, W Lu, Y Jiang, J Wang - Journal of translational medicine, 2018 - Springer
Abstract Triple Negative Breast Cancer (TNBC) is a highly heterogeneous subtype of breast
cancer that lacks the expression of oestrogen receptors, progesterone receptors and human …

Immunotherapy for triple-negative breast cancer: Existing challenges and exciting prospects

H Jia, CI Truica, B Wang, Y Wang, X Ren… - Drug resistance …, 2017 - Elsevier
Patients with breast tumors that do not express the estrogen receptor, the progesterone
receptor, nor Her-2/neu are hence termed “triple negatives”, and generally have a poor …

The emerging role of immune checkpoint inhibitors in the treatment of triple-negative breast cancer

S Singh, A Numan, B Maddiboyina, S Arora, Y Riadi… - Drug discovery today, 2021 - Elsevier
Highlights•TNBCs is one of the most heterogenous form of breast cancer appear to have
elevated numbers of immune cells infiltration.•Using immune checkpoint inhibitors (ICIs) …

Progress and challenges of immunotherapy in triple-negative breast cancer

Y Zhu, X Zhu, C Tang, X Guan, W Zhang - Biochimica et Biophysica Acta …, 2021 - Elsevier
Triple-negative breast cancer (TNBC), a subtype of breast cancer, is defined as lacking
estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor …

Progress and pitfalls in the use of immunotherapy for patients with triple negative breast cancer

E Agostinetto, A Losurdo, G Nader-Marta… - Expert opinion on …, 2022 - Taylor & Francis
Introduction Triple negative breast cancer (TNBC) is an area of high unmet medical need in
terms of new effective treatment strategies. Although breast cancer is traditionally …

Clinical trials of immunotherapy in triple-negative breast cancer

FM Howard, AT Pearson, R Nanda - Breast Cancer Research and …, 2022 - Springer
Purpose Immunotherapy has started to transform the treatment of triple-negative breast
cancer (TNBC), in part due to the unique immunogenicity of this breast cancer subtype. This …