Harnessing anti-inflammatory pathways and macrophage nano delivery to treat inflammatory and fibrotic disorders

A Zaid, A Ariel - Advanced Drug Delivery Reviews, 2024 - Elsevier
Targeting specific organs and cell types using nanotechnology and sophisticated delivery
methods has been at the forefront of applicative biomedical sciences lately. Macrophages …

Role of macrophage in nanomedicine-based disease treatment

S Song, H Xia, M Guo, S Wang, S Zhang, P Ma… - Drug delivery, 2021 - Taylor & Francis
Macrophages are a major component of the immunoresponse. Diversity and plasticity are
two of the hallmarks of macrophages, which allow them to act as proinflammatory, anti …

Drug delivery to macrophages: A review of nano-therapeutics targeted approach for inflammatory disorders and cancer

M Mukhtar, H Ali, N Ahmed, R Munir… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction Macrophages are involved in the normal defense of the body; however, the
varying phenotypes of macrophages and imbalance in their ratio lead to the impairment of …

Advancements in macrophage-targeted drug delivery for effective disease management

H Liu, H Lv, X Duan, Y Du, Y Tang… - International Journal of …, 2023 - Taylor & Francis
Macrophages play a crucial role in tissue homeostasis and the innate immune system. They
perform essential functions such as presenting antigens, regulating cytokines, and …

Nanomedicines for dysfunctional macrophage-associated diseases

H He, S Ghosh, H Yang - Journal of Controlled Release, 2017 - Elsevier
Macrophages play vital functions in host inflammatory reaction, tissue repair, homeostasis
and immunity. Dysfunctional macrophages have significant pathophysiological impacts on …

[HTML][HTML] Nanomaterials manipulate macrophages for rheumatoid arthritis treatment

S Li, J Su, W Cai, J Liu - Frontiers in Pharmacology, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic, progressive, and systemic inflammatory autoimmune
disease, characterized by synovial inflammation, synovial lining hyperplasia and …

Advanced nanomedicines for the treatment of inflammatory diseases

R Brusini, M Varna, P Couvreur - Advanced drug delivery reviews, 2020 - Elsevier
Inflammation, a common feature of many diseases, is an essential immune response that
enables survival and maintains tissue homeostasis. However, in some conditions, the …

Multivalent nanosystems: targeting monocytes/macrophages

R Poupot, C Goursat, S Fruchon - International Journal of …, 2018 - Taylor & Francis
Among all the cellular partners involved in inflammatory processes, monocytes and
macrophages are the master regulators of inflammation. They are found in almost all the …

Active nano-targeting of macrophages

N Gaspar, G Zambito, CMWG Löwik… - Current …, 2019 - ingentaconnect.com
Macrophages play a role in almost every disease such as cancer, infections, injuries,
metabolic and inflammatory diseases and are becoming an attractive therapeutic target …

Protein based nanomedicine: Promising therapeutic modalities against inflammatory disorders

Y Zaheer, T Vorup‐Jensen, TJ Webster, M Ahmed… - Nano …, 2022 - Wiley Online Library
The safe and targeted delivery of pharmaceutical formulations has relied extensively on
synthetic chemistry and other physicochemical approaches. The research paradigm is now …