This study was to investigate whether sulforaphane (SFN) can prevent diabetic
cardiomyopathy. Type 1 diabetes was induced in FVB mice by multiple intraperitoneal …

Aims Activation of nuclear factor erythroid 2-related factor 2 (Nrf2) by sulforaphane (SFN)
protects from, and deletion of the Nrf2 gene exaggerates, diabetic cardiomyopathy …

We have reported that sulforaphane (SFN) prevented diabetic cardiomyopathy in both type 1
and type 2 diabetes (T2DM) animal models via the upregulation of nuclear transcription …

To develop a clinic-relevant protocol for systemic up-regulation of NFE2-related factor 2
(Nrf2) to prevent diabetic cardiomyopathy (DCM), male db/db and age-matched wild-type …

Background AMP-activated protein kinase (AMPK), particularly AMPKα2 isoform, plays a
critical role in maintaining cardiac homeostasis. It was reported that sulforaphane (SFN) …

Objective. This study investigated if resveratrol ameliorates diabetic cardiomyopathy by
targeting associated oxidative stress mechanisms. Method. Type 1 diabetes mellitus (DM) in …

Type 2 diabetes mellitus (T2DM)-induced cardiomyopathy is associated with cardiac
oxidative stress, inflammation, and remodeling. Sulforaphane (SFN), an isothiocyanate …

Diabetic cardiomyopathy (DCM), as one of the major cardiac complications in diabetic
patients, is known to related with oxidative stress that is due to a severe imbalance between …

Background Doxorubicin (DOX) is an anthracycline antitumor drug. However, its clinical use
is limited by dose‐dependent cardiotoxicity and even progresses to chronic heart failure …

Diabetic cardiomyopathy is one of the main causes of heart failure and death in patients with
diabetes mellitus. Reactive oxygen species produced excessively in diabetes mellitus cause …