Melanin dependent survival of Apergillus fumigatus conidia in lung epithelial cells
S Amin, A Thywissen, T Heinekamp, HP Saluz… - International Journal of …, 2014 - Elsevier
Aspergillus fumigatus is the most important air-borne pathogenic fungus of humans. Upon
inhalation of conidia, the fungus makes close contact with lung epithelial cells, which only …
inhalation of conidia, the fungus makes close contact with lung epithelial cells, which only …
Conidial Dihydroxynaphthalene Melanin of the Human Pathogenic Fungus Aspergillus fumigatus Interferes with the Host Endocytosis Pathway
A Thywißen, T Heinekamp, HM Dahse… - Frontiers in …, 2011 - frontiersin.org
Aspergillus fumigatus is the most important air-borne fungal pathogen of humans. The
interaction of the pathogen with the host's immune system represents a key process to …
interaction of the pathogen with the host's immune system represents a key process to …
Hide, Keep Quiet, and Keep Low: Properties That Make Aspergillus fumigatus a Successful Lung Pathogen
N Escobar, SR Ordonez, HAB Wösten… - Frontiers in …, 2016 - frontiersin.org
Representatives of the genus Aspergillus are opportunistic fungal pathogens. Their conidia
can reach the alveoli by inhalation and can give rise to infections in immunocompromised …
can reach the alveoli by inhalation and can give rise to infections in immunocompromised …
Human Bronchial Epithelial Cells Inhibit Aspergillus fumigatus Germination of Extracellular Conidia via FleA Recognition
N Richard, L Marti, A Varrot, L Guillot, J Guitard… - Scientific reports, 2018 - nature.com
Aspergillus fumigatus is an environmental filamentous fungus that may act as an
opportunistic pathogen causing a variety of diseases, including asthma or allergic …
opportunistic pathogen causing a variety of diseases, including asthma or allergic …
Uptake of Aspergillus fumigatus Conidia by Phagocytic and Nonphagocytic Cells In Vitro: Quantitation Using Strains Expressing Green Fluorescent Protein
JA Wasylnka, MM Moore - Infection and immunity, 2002 - Am Soc Microbiol
Several pathogenic fungal organisms enter eukaryotic cells and manipulate the host cell
environment to favor their own growth and survival. Aspergillus fumigatus is a saprophytic …
environment to favor their own growth and survival. Aspergillus fumigatus is a saprophytic …
Phagocytosis of Aspergillus fumigatus conidia by primary nasal epithelial cells in vitro
F Botterel, K Gross, O Ibrahim-Granet, K Khoufache… - BMC microbiology, 2008 - Springer
Background Invasive aspergillosis, which is mainly caused by the fungus Aspergillus
fumigatus, is an increasing problem in immunocompromised patients. Infection occurs by …
fumigatus, is an increasing problem in immunocompromised patients. Infection occurs by …
Pulmonary immune responses to Aspergillus fumigatus in an immunocompetent mouse model of repeated exposures
AD Buskirk, SP Templeton, AP Nayak… - Journal of …, 2014 - Taylor & Francis
Aspergillus fumigatus is a filamentous fungus that produces abundant pigmented conidia.
Several fungal components have been identified as virulence factors, including melanin; …
Several fungal components have been identified as virulence factors, including melanin; …
Phagocytosis of melanized Aspergillus conidia by macrophages exerts cytoprotective effects by sustained PI3K/Akt signalling
K Volling, A Thywissen, AA Brakhage… - Cellular …, 2011 - Wiley Online Library
Host cell death is a critical component of innate immunity and often determines the
progression and outcome of infections. The opportunistic human pathogen Aspergillus …
progression and outcome of infections. The opportunistic human pathogen Aspergillus …
Expression profile analysis reveals that Aspergillus fumigatus but not Aspergillus niger makes type II epithelial lung cells less immunological alert
N Escobar, ID Valdes, EM Keizer, SR Ordonez… - BMC genomics, 2018 - Springer
Background Aspergillus fumigatus is the main causative agent of aspergillosis. Infections
rarely occur in immunocompetent individuals, indicating efficient clearance of conidia by …
rarely occur in immunocompetent individuals, indicating efficient clearance of conidia by …
Proteomics of Aspergillus fumigatus conidia-containing phagolysosomes identifies processes governing immune evasion
H Schmidt, S Vlaic, T Krüger, F Schmidt… - Molecular & Cellular …, 2018 - ASBMB
Invasive infections by the human pathogenic fungus Aspergillus fumigatus start with the
outgrowth of asexual, airborne spores (conidia) into the lung tissue of immunocompromised …
outgrowth of asexual, airborne spores (conidia) into the lung tissue of immunocompromised …