Nonadrenergic noncholinergic nerves regulate basal coronary flow via release of capsaicin-sensitive neuropeptides in the rat heart.

H Yaoita, E Sato, M Kawaguchi, T Saito… - Circulation …, 1994 - Am Heart Assoc
Nonadrenergic noncholinergic nerve fibers supposedly modulate basal coronary flow by
releasing capsaicin-sensitive neuropeptides, but the physiological effects of this intrinsic …

Capsaicin‐induced vasodilatation of human coronary arteries in vitro is mediated by calcitonin gene‐related peptide rather than substance P or neurokinin A

A Franco‐Cereceda, A Rudehill - Acta physiologica …, 1989 - Wiley Online Library
In the present study the possible influence of capsaicin on human arterial coronary tone in
vitro was studied in relation to the vasodilatory properties of calcitonin gene‐related peptide …

Role of nitric oxide in the dilator actions of capsaicin-sensitive nerves in the rabbit coronary circulation

JA Mitchell, FM Williams, TJ Williams, SW Larkin - Neuropeptides, 1997 - Elsevier
Perivascular sensory nerves release calcitonin gene-related peptide (CGRP) and substance
P, the dilator actions of which can be regulated by nitric oxide (NO). This study investigated …

Arachidonic acid and bradykinin share a common pathway to release neuropeptide from capsaicin-sensitive sensory nerve fibers of the guinea pig heart.

P Geppetti, E Del Bianco, M Tramontana… - … of Pharmacology and …, 1991 - ASPET
The ability of arachidonic acid (AA) and bradykinin to release calcitonin gene-related
peptide-like immunoreactivity (CGRP-LI) from capsaicin-sensitive primary afferents was …

Calcitonin gene-related peptide but not substance P mimics capsaicin-induced coronary vasodilation in the pig

A Franco-Cereceda, A Rudehill… - European journal of …, 1987 - Elsevier
The vasodilator effects of the human calcitonin gene-related peptides α (hCGRPα) and β
(hCGRPβ) were studied in vitro and in vivo in relation to the effects of substance P (SP) and …

A comparison of bradykinin‐and capsaicin‐induced myocardial and coronary effects in isolated perfused heart of guinea‐pig: involvement of substance P and …

S Manzini, F Perretti, L de Benedetti… - British journal of …, 1989 - Wiley Online Library
1 Bradykinin and capsaicin were compared for their ability to elicit functional effects and to
release sensory neuropeptides from guinea‐pig isolated perfused hearts. 2 Both bradykinin …

Calcitonin gene-related peptide and tachykinins in relation to local sensory control of cardiac contractility and coronary vascular tone.

A Franco-Cereceda - Acta physiologica Scandinavica …, 1988 - europepmc.org
The possible role of peptides locally released from sensory nerves in the control of cardiac
contractility and the coronary vascular tone was investigated in the present study …

Interplay between nitric oxide and CGRP by capsaicin in isolated guinea-pig heart

G OROSZI, Z SZILVASSY, J NEMETH, A TOSAKI… - Pharmacological …, 1999 - Elsevier
Capsaicin at a concentration of 10− 7m induced a significant increase in heart rate and
increased coronary flow in isolated Langendorff-perfused guinea-pig hearts. This effect was …

Heterogeneous involvement of endothelium in calcitonin gene-related peptide-induced relaxation in coronary arteries from rat.

D Prieto, S Benedito, NC Nyborg - British journal of pharmacology, 1991 - ncbi.nlm.nih.gov
The effects of rat-and human-CGRP and capsaicin were studied in isolated rings of rat
proximal epicardial (PC) and distal intramyocardial (DC) coronary arteries. 2. The relaxing …

Modulation of coronary flow and cardiomyocyte size by sensory fibers

A Zanesco, SKP Costa, SR Riado, LP Nathan… - …, 1999 - Am Heart Assoc
Cardiac tissue is densely innervated by sensory neurons that are believed to play important
modulatory roles in cardiac functions. In this study, pretreatment of neonate rats with …