Crosstalk between adenylyl cyclase signaling pathway and Ca 2+ regulatory mechanism under red blood cell microrheological changes

AV Muravyov, IA Tikhomirova… - Clinical …, 2010 - content.iospress.com
There are evidences that red blood cell (RBC) deformation and aggregation change under
their incubation with catecholamines and it is connected with activation of intracellular …

Extra-and intracellular signaling pathways under red blood cell aggregation and deformability changes

AV Muravyov, IA Tikhomirova… - Clinical …, 2009 - content.iospress.com
Exposure of red blood cells (RBCs) to catecholamines (epinephrine, phenylephrine, an
agonist of α 1-adrenergic receptors, clonidine, an agonist of α 2-adrenergic receptors and …

Role Ca2+ in Mechanisms of the Red Blood Cells Microrheological Changes

A Muravyov, I Tikhomirova - Calcium signaling, 2012 - Springer
To assess the physiological role of intracellular Ca 2+ in the changes of microrheological
red blood cell (RBC) properties (RBC deformability and aggregation), we employed several …

Role molecular signaling pathways in changes of red blood cell deformability

AV Muravyov, IA Tikhomirova - Clinical hemorheology and …, 2013 - content.iospress.com
This study was designed to investigate the dependency of the red blood cell deformability
upon activation of extra-and intracellular signaling pathways. Exposures of red blood cells …

The effects of different signaling pathways in adenylyl cyclase stimulation on red blood cells deformability

AN Semenov, EA Shirshin, AV Muravyov… - Frontiers in …, 2019 - frontiersin.org
Signaling pathways of red blood cells'(RBCs) micromechanics regulation, which are
responsible for maintaining microcirculation, constitute an important property of RBC …

Signaling pathways regulating red blood cell aggregation

A Muravyov, I Tikhomirova - Biorheology, 2014 - content.iospress.com
The exposure of red blood cells (RBC) to some hormones (epinephrine, insulin and
glucagon) and agonists of α-and β-adrenergic receptors (phenylephrine, clonidine and …

Macro-and microrheological parameters of blood in patients with cerebral and peripheral atherosclerosis: the molecular change mechanisms after pentoxifylline …

AV Muravyov, SV Bulaeva… - Clinical …, 2011 - content.iospress.com
This study was designed to evaluate hemorheological changes in patients with
cerebrovascular disease (CVD) and peripheral arterial disease (PAD) after 4 weeks of …

Red blood cell aggregation changes are depended on its initial value: Effect of long-term drug treatment and short-term cell incubation with drug

AV Muravyov, IA Tikhomirova… - Clinical …, 2011 - content.iospress.com
This study was designed to investigate whether the red cell aggregation depends on its
initial level under drug therapy or cell incubation with bioactive chemical compounds. Sixty …

Erythrocyte deformability and eryptosis during inflammation, and impaired blood rheology

E Pretorius - Clinical hemorheology and microcirculation, 2018 - content.iospress.com
OBJECTIVE: This review focusses on the erythrocytes (RBCs) and their structural changes
during inflammation and impaired blood rheology. We discuss systemic inflammation and …

Proteomic analysis of the role of the adenylyl cyclase–cAMP pathway in red blood cell mechanical responses

E Ugurel, E Goksel, N Cilek, E Kaga, O Yalcin - Cells, 2022 - mdpi.com
Red blood cell (RBC) deformability is modulated by the phosphorylation status of the
cytoskeletal proteins that regulate the interactions of integral transmembrane complexes …