Nanoparticle delivery systems have been extensively investigated for targeted delivery of
anticancer drugs over the past decades. However, it is still a great challenge to overcome …

Seeman's pioneer idea has led to the foundation of DNA nanostructures, resulting in a
remarkable advancement in DNA nanotechnology. Over the last few decades, remarkable …

DNA assembly has provided new opportunities for the development of a novel drug delivery
system (DDS) for real-time monitoring and precision treatment of cancer lesions. Herein, we …

Deoxyribonucleic acid (DNA) is a versatile material with high applicability and inherent
biocompatibility. L-DNA, the perfect mirror form of the naturally occurring D-DNA, has been …

Nanostructures based on DNA self‐assembly present an innovative way to address the
increasing need for target‐specific delivery of therapeutic molecules. Currently, most of the …

In cancer therapy, it is imperative to increase the efficacy and reduce side effects of
chemotherapeutic drugs. Nanotechnology offers the unique opportunity to overcome these …

DNA nanoparticles have been proposed for drug encapsulation and intracellular delivery,
but it has remained a challenge to rationally design DNA nanoparticles for delivery of drug to …

A proper intracellular delivery method with target tissue specificity is critical to utilize the full
potential of therapeutic molecules including siRNAs while minimizing their side effects …

Self-assembled DNA nanostructures have attracted significant research interest in
biomedical applications because of their excellent programmability and biocompatibility. To …

Many chemotherapeutics used for cancer treatments encounter issues during delivery to
tumors in vivo and may have high levels of systemic toxicity due to their nonspecific …