Haematopoietic stem cell activity and interactions with the niche
S Pinho, PS Frenette - Nature reviews Molecular cell biology, 2019 - nature.com
The haematopoietic stem cell (HSC) microenvironment in the bone marrow, termed the
niche, ensures haematopoietic homeostasis by controlling the proliferation, self-renewal …
niche, ensures haematopoietic homeostasis by controlling the proliferation, self-renewal …
Adult haematopoietic stem cell niches
Stem cell niches are specialized microenvironments that promote the maintenance of stem
cells and regulate their function. Recent advances have improved our understanding of the …
cells and regulate their function. Recent advances have improved our understanding of the …
[HTML][HTML] The evolving view of the hematopoietic stem cell niche
Highlights•The hematopoietic stem cell niche is a dynamic and complex environment.•
Summary of a webinar lead and moderated by experts of this topic.Hematopoietic stem cells …
Summary of a webinar lead and moderated by experts of this topic.Hematopoietic stem cells …
Bone marrow niches of hematopoietic stem and progenitor cells
O Kandarakov, A Belyavsky, E Semenova - International Journal of …, 2022 - mdpi.com
The mammalian hematopoietic system is remarkably efficient in meeting an organism's vital
needs, yet is highly sensitive and exquisitely regulated. Much of the organismal control over …
needs, yet is highly sensitive and exquisitely regulated. Much of the organismal control over …
Making sense of hematopoietic stem cell niches
PE Boulais, PS Frenette - Blood, The Journal of the American …, 2015 - ashpublications.org
The hematopoietic stem cell (HSC) niche commonly refers to the pairing of hematopoietic
and mesenchymal cell populations that regulate HSC self-renewal, differentiation, and …
and mesenchymal cell populations that regulate HSC self-renewal, differentiation, and …
The HSC niche concept has turned 31: has our knowledge matured?
S Lymperi, F Ferraro… - Annals of the New York …, 2010 - Wiley Online Library
The hematopoietic stem cell (HSC) niche is currently defined as the specific
microenvironment in the bone marrow (BM) which anatomically harbors HSCs and governs …
microenvironment in the bone marrow (BM) which anatomically harbors HSCs and governs …
The haematopoietic stem cell niche at a glance
C Lo Celso, DT Scadden - Journal of cell science, 2011 - journals.biologists.com
ARTICLE SERIES: Stem Cells Cell Science at a Glance 3529 dormancy (Trumpp et al.,
2010) and, thereby, maintain homeostasis both in the steady state as well as in response to …
2010) and, thereby, maintain homeostasis both in the steady state as well as in response to …
[HTML][HTML] The hematopoietic stem cell niche
Hematopoietic stem cells (HSCs) possess the ability to self-renew and to differentiate to
mature progeny along multiple different hematopoietic lineages. The function of HSCs …
mature progeny along multiple different hematopoietic lineages. The function of HSCs …
The hematopoietic bone marrow niche ecosystem
J Fröbel, T Landspersky, G Percin… - Frontiers in cell and …, 2021 - frontiersin.org
The bone marrow (BM) microenvironment, also called the BM niche, is essential for the
maintenance of fully functional blood cell formation (hematopoiesis) throughout life. Under …
maintenance of fully functional blood cell formation (hematopoiesis) throughout life. Under …
Hematopoietic stem cell niche maintenance during homeostasis and regeneration
A Mendelson, PS Frenette - Nature medicine, 2014 - nature.com
The bone marrow niche has mystified scientists for many years, leading to widespread
investigation to shed light into its molecular and cellular composition. Considerable efforts …
investigation to shed light into its molecular and cellular composition. Considerable efforts …