Idiopathic pulmonary fibrosis (IPF) is a representative disease that causes fibrosis of the
lungs. Its pathogenesis is thought to be characterized by sustained injury to alveolar …

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease of unknown etiology
characterized by distorted distal lung architecture, inflammation, and fibrosis. The molecular …

Idiopathic pulmonary fibrosis (IPF) is a progressive disease with significant mortality.
Prognostic biomarkers to identify rapid progressors are urgently needed to improve patient …

Pulmonary fibrosis (PF) can be idiopathic or driven by a specific insult or disease process.
Inflammation plays a role in the pathophysiology, the extent of which remains a longstanding …

Background Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease with no
effective medical therapies. Recent research has focused on identifying the biological …

Idiopathic pulmonary fibrosis (IPF) is characterized by progressive extracellular matrix
deposition in the lung parenchyma leading to the destruction of lung structure, respiratory …

There has been great recent interest in the bioactive lipid mediator lysophosphatidic acid
(LPA) in the pathogenesis of fibrotic diseases, from both academic laboratories and …

Lysophosphatidic acid (LPA) and its G protein-coupled receptor (LPA1) play key pathogenic
roles in idiopathic pulmonary fibrosis (IPF). Previous research has highlighted the …

Idiopathic pulmonary fibrosis (IPF) is a chronic irreversible interstitial lung disease
characterized by a progressive decline in lung function. The etiology of IPF is unknown …

Fatty acid metabolism, including the de novo synthesis, uptake, oxidation, and derivation of
fatty acids, plays several important roles at cellular and organ levels. Recent studies have …