Diabetes mellitus is a group of diseases characterized by hyperglycemia and its
consequences, affecting over 34 million individuals in the United States and 422 million …

Most diabetes is polygenic in etiology, with (type 1 diabetes, T1DM) or without (type 2
diabetes, T2DM) an autoimmune basis. Genetic counseling for diabetes generally focuses …

Individualization of therapy based on a person's specific type of diabetes is one key element
of a “precision medicine” approach to diabetes care. However, applying such an approach …

Monogenic diabetes is a category of diabetes mellitus caused by a single gene mutation or
chromosomal abnormality, usually sub-classified as either neonatal diabetes or maturity …

Monogenic forms of diabetes are responsible for 1-3% of all young-onset diabetes. The
multiple genes involved can cause one or both of the main phenotypes-congenital …

Although there have been clinical and genetic advances in monogenic diabetes, patients
are still misdiagnosed. Improved insurance coverage of genetic testing is needed. The …

Abstract Purpose of Review Monogenic forms of diabetes have specific treatments that differ
from the standard care provided for type 1 and type 2 diabetes, making the appropriate …

Background: Monogenic diabetes is a group of disorders caused by mutations in any one of
a number of genes. Although a monogenic diagnosis—estimated to represent as much as …

Background Monogenic diabetes presents opportunities for precision medicine but is
underdiagnosed. This review systematically assessed the evidence for (1) clinical criteria …

Monogenic diabetes results from inheritance of one or more mutations in a single gene and
accounts for 1–3% of diabetes cases diagnosed< 30 years. Mutations may be inherited in a …