Therapeutic effect of demethylated hydroxylated phillygenin derivative on Helicobacter pylori infection

RJ Li, J Xu, X Wang, L Liao, X Wei, P Xie… - Frontiers in …, 2023 - frontiersin.org
Modifying and transforming natural antibacterial products is a novel idea for developing new
efficacious compounds. Phillygenin has an inhibitory effect on H. pylori. The aim of the …

Phillygenin Inhibits Helicobacter pylori by Preventing Biofilm Formation and Inducing ATP Leakage

RJ Li, C Qin, GR Huang, LJ Liao, XQ Mo… - Frontiers in …, 2022 - frontiersin.org
With the widespread use and abuse of antibiotics, Helicobacter pylori (H. pylori) has become
seriously drug resistant. The development of new antibiotics is an important way to solve H …

In vitro anti-Helicobacter pylori activity and the underlining mechanism of an empirical herbal formula – Hezi Qingyou

Z Feng, H Li, Y Hao, C Peng, L Ou, J Jia… - Frontiers in …, 2024 - frontiersin.org
Background Helicobacter pylori (H. pylori) is thought to primarily colonize the human
stomach and lead to various gastrointestinal disorders, such as gastritis and gastric cancer …

Urolithin B alleviates Helicobacter pylori‐induced inflammation and oxidative stress in mice

Z Yu, X Zhang, Q Zhao, X Yan, C Wu, L Qing… - …, 2023 - Wiley Online Library
Background Helicobacter pylori is one of the most common chronic bacterial infections.
Active eradication of H. pylori infection is rare due to the fact that most infected patients are …

Eradication of Helicobacter pylori through the inhibition of urease and peptide deformylase: Computational and biological studies

K Saravanakumar, R Chellia, X Hu, K Kathiresan… - Microbial …, 2019 - Elsevier
This work tested anti-Helicobacter pylori, free radicals scavenging and toxicity property as
well as chemical constituents in the extract of chloroform (CE) and ethyl acetate (EAE) from …

Loureirin A is a narrow-spectrum antimicrobial agent against Helicobacter pylori

Q Tong, C Yin, X Hang, Y Bai, C Zhang… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Currently, Helicobacter pylori eradication by antibiotic therapy faces various challenges,
including antibiotic resistance, side effects on intestinal commensal bacteria, and patient …

The antibacterial mode of action of allitridi for its potential use as a therapeutic agent against Helicobacter pylori infection

S Liu, Y Sun, W Li, H Yu, X Li, Z Liu… - FEMS microbiology …, 2010 - academic.oup.com
Eradication of Helicobacter pylori with traditional therapy often fails in clinical treatment. As a
result, a novel efficacious therapeutic agent is strongly needed. Allitridi, a proprietary garlic …

In Silico Screening and In Vitro Assessment of Natural Products with Anti-Virulence Activity against Helicobacter pylori

M Spiegel, P Krzyżek, E Dworniczek, R Adamski… - Molecules, 2021 - mdpi.com
Helicobacter pylori is one of the most frequent human pathogens and a leading etiological
agent of various gastric diseases. As stringent response, coordinated by a SpoT protein …

Daphnetin: A Novel Anti-Helicobacter pylori Agent

G Wang, J Pang, X Hu, T Nie, X Lu, X Li… - International journal of …, 2019 - mdpi.com
Background: Antibiotic-resistant H. pylori was increasingly found in infected individuals,
which resulted in treatment failure and required alternative therapeutic strategies …

Quantitative proteomics approach to investigate the antibacterial response of Helicobacter pylori to daphnetin, a traditional Chinese medicine monomer

Y Lu, J Pang, G Wang, X Hu, X Li, G Li, X Wang… - RSC …, 2021 - pubs.rsc.org
Helicobacter pylori is a Gram-negative bacterium related to the development of peptic ulcers
and stomach cancer. An increasing number of infected individuals are found to harbor …