Effects of surface smoothness on inertial particle deposition in human nasal models

JD Schroeter, GJM Garcia, JS Kimbell - Journal of aerosol science, 2011 - Elsevier
Computational fluid dynamics (CFD) predictions of inertial particle deposition have not
compared well with data from nasal replicas due to effects of surface texture and the …

Particle deposition in human nasal airway replicas manufactured by different methods. Part I: Inertial regime particles

JT Kelly, B Asgharian, JS Kimbell… - Aerosol science and …, 2004 - Taylor & Francis
Information on the deposition efficiency of aerosol particles in the nasal airways is used for
optimizing the delivery of therapeutic aerosols into the nose and for risk assessment of toxic …

Numerical predictions of submicrometer aerosol deposition in the nasal cavity using a novel drift flux approach

J Xi, PW Longest - International Journal of Heat and Mass Transfer, 2008 - Elsevier
Evaluating the health effects of inhaled submicrometer aerosols, such as combustion
particulate matter and bioaerosols, requires a thorough understanding of transport and …

Unsteady particle tracking of micro-particle deposition in the human nasal cavity under cyclic inspiratory flow

H Bahmanzadeh, O Abouali, G Ahmadi - Journal of Aerosol Science, 2016 - Elsevier
In this study, a fully unsteady computational fluid dynamics (CFD) model was used and the
transient airflow properties during the entire breathing cycle, including inhalation and …

Particle deposition in human nasal airway replicas manufactured by different methods. Part II: Ultrafine particles

JT Kelly, B Asgharian, JS Kimbell… - Aerosol science and …, 2004 - Taylor & Francis
Information on the deposition of ultrafine particles in nasal airways is important for assessing
the risks of exposure to airborne particulate matter and for understanding drug delivery …

Modeling of inertial deposition in scaled models of rat and human nasal airways: Towards in vitro regional dosimetry in small animals

J Xi, JW Kim, XA Si, RA Corley, Y Zhou - Journal of Aerosol Science, 2016 - Elsevier
Rodents are routinely used in inhalation toxicology tests as human surrogates. However, in
vitro dosimetry tests in rodent casts are still scarce due to small rodent airways and in vitro …

Empirical equations for nasal deposition of inhaled particles in small laboratory animals and humans

L Zhang, CP Yu - Aerosol science and technology, 1993 - Taylor & Francis
Based upon available experimental data, a set of empirical equations was derived for nasal
deposition efficiency of inhaled particles in the inertial deposition range for four small …

Human nasal passage particle deposition: the effect of particle size, flow rate, and anatomical factors

J Kesavanathan, DL Swift - Aerosol science and technology, 1998 - Taylor & Francis
This study determined the effect of particle size, flow rate, nostril shape, and nasal passage
geometry on nasal particle deposition efficiency (PDE) in ten healthy, nonsmoking adults …

Modeling of inertial particle transport and deposition in human nasal cavities with wall roughness

H Shi, C Kleinstreuer, Z Zhang - Journal of Aerosol Science, 2007 - Elsevier
Nasal inhalation helps to protect the lungs from detrimental effects of toxic particles which,
however, may also place the nasal and adjacent tissues at risk. Alternatively, drug–aerosol …

Detailed micro-particle deposition patterns in the human nasal cavity influenced by the breathing zone

YD Shang, K Inthavong, JY Tu - Computers & Fluids, 2015 - Elsevier
The breathing region connects the nasal cavity with the outside environmental air where
flow is accelerated through the nostrils. Particles introduced into the nasal cavity without …