Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination
MD Larsen, M Lopez-Perez, EK Dickson… - Nature …, 2021 - nature.com
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family members mediate
receptor-and tissue-specific sequestration of infected erythrocytes (IEs) in malaria. Antibody …
receptor-and tissue-specific sequestration of infected erythrocytes (IEs) in malaria. Antibody …
Targets of antibodies against Plasmodium falciparum–infected erythrocytes in malaria immunity
Plasmodium falciparum is the major cause of malaria globally and is transmitted by
mosquitoes. During parasitic development, P. falciparum–infected erythrocytes (P …
mosquitoes. During parasitic development, P. falciparum–infected erythrocytes (P …
Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1
L Barfod, MB Dalgaard, ST Pleman… - Proceedings of the …, 2011 - National Acad Sciences
Plasmodium falciparum malaria is a major cause of mortality and severe morbidity. Its
virulence is related to the parasite's ability to evade host immunity through clonal antigenic …
virulence is related to the parasite's ability to evade host immunity through clonal antigenic …
α2-Macroglobulin Can Crosslink Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Molecules and May Facilitate Adhesion of Parasitized …
L Stevenson, E Laursen, GJ Cowan, B Bandoh… - PLoS …, 2015 - journals.plos.org
Rosetting, the adhesion of Plasmodium falciparum-infected erythrocytes to uninfected
erythrocytes, involves clonal variants of the parasite protein P. falciparum erythrocyte …
erythrocytes, involves clonal variants of the parasite protein P. falciparum erythrocyte …
Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates
Understanding the targets and mechanisms of human immunity to malaria caused by
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …
Antibody Targets on the Surface of Plasmodium falciparum–Infected Erythrocytes That Are Associated With Immunity to Severe Malaria in Young Children
Abstract Background Sequestration of Plasmodium falciparum–infected erythrocytes (IEs) in
the microvasculature contributes to pathogenesis of severe malaria in children. This …
the microvasculature contributes to pathogenesis of severe malaria in children. This …
Investigating the function of Fc‐specific binding of IgM to Plasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting
L Stevenson, P Huda, A Jeppesen… - Cellular …, 2015 - Wiley Online Library
Acquired protection from P lasmodium falciparum malaria takes years to develop, probably
reflecting the ability of the parasites to evade immunity. A recent example of this is the …
reflecting the ability of the parasites to evade immunity. A recent example of this is the …
Plasmodium falciparum erythrocyte membrane protein-1 specifically suppresses early production of host interferon-γ
MC D'Ombrain, TS Voss, AG Maier, JA Pearce… - Cell host & …, 2007 - cell.com
Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP-1) is a variable antigen
expressed by P. falciparum, the malarial parasite. PfEMP-1, present on the surface of …
expressed by P. falciparum, the malarial parasite. PfEMP-1, present on the surface of …
Regulation of immune response by Plasmodium‐infected red blood cells
During the asexual blood stage infection of the human malaria parasite, Plasmodium
falciparum, parasite‐derived proteins are inserted onto the surface of the host red blood cell …
falciparum, parasite‐derived proteins are inserted onto the surface of the host red blood cell …
Identification of residues in the Cμ4 domain of polymeric IgM essential for interaction with Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1)
A Ghumra, JP Semblat, RS McIntosh… - The Journal of …, 2008 - journals.aai.org
The binding of nonspecific human IgM to the surface of infected erythrocytes is important in
rosetting, a major virulence factor in the pathogenesis of severe malaria due to Plasmodium …
rosetting, a major virulence factor in the pathogenesis of severe malaria due to Plasmodium …