[HTML][HTML] Polyunsaturated fatty acid–cholesterol interactions: domain formation in membranes

SR Wassall, W Stillwell - Biochimica et Biophysica Acta (BBA) …, 2009 - Elsevier
Polyunsaturated fatty acids (PUFA) constitute an influential group of molecules that promote
health by an as yet unknown mechanism. They are structurally distinguished from less …

The nutritional significance of lipid rafts

P Yaqoob - Annual review of nutrition, 2009 - annualreviews.org
The structure, size, stability, and functionality of lipid rafts are still in debate, but recent
techniques allowing direct visualization have characterized them in a wide range of cell …

Polyunsaturated lipids regulate membrane domain stability by tuning membrane order

KR Levental, JH Lorent, X Lin, AD Skinkle, MA Surma… - Biophysical journal, 2016 - cell.com
The plasma membrane (PM) serves as the functional interface between a cell and its
environment, hosting extracellular signal transduction and nutrient transport among a variety …

Effects of dietary n− 3 polyunsaturated fatty acids on T-cell membrane composition and function

KC Switzer, DN McMurray, RS Chapkin - Lipids, 2004 - Springer
Dietary n− 3 PUFA have been shown to attenuate T-cell-mediated inflammation, in part, by
suppressing T-cell activation and proliferation. n− 3 PUFA have also been shown to promote …

Bioactive dietary long-chain fatty acids: emerging mechanisms of action

RS Chapkin, DN McMurray, LA Davidson… - British Journal of …, 2008 - cambridge.org
The plasma membranes of all eukaryotic cells contain heterogeneous self-organising
intrinsically unstable liquid ordered domains or lipid assemblies in which key signal …

Docosahexaenoic acid domains: the ultimate non-raft membrane domain

SR Wassall, W Stillwell - Chemistry and physics of lipids, 2008 - Elsevier
What distinguishes polyunsaturated fatty acids (PUFAs) from less unsaturated fatty acids is
the presence of a repeating CH–CH2–CH unit that produces an extremely flexible structure …

The role of polyunsaturated lipids in membrane raft function

W Stillwell - Scandinavian Journal of Food and Nutrition, 2006 - Taylor & Francis
Abstract Docosahexaenoic acid (DHA), with 22 carbons and six double bonds, is the
longest, most unsaturated fatty acid commonly found in humans. It represents the extreme …

Dietary omega‐3 PUFA and health: Stearidonic acid‐containing seed oils as effective and sustainable alternatives to traditional marine oils

ME Surette - Molecular Nutrition & Food Research, 2013 - Wiley Online Library
The daily consumption of dietary omega‐3 PUFA is recommended by governmental
agencies in several countries and by a number of health organizations. The molecular …

[HTML][HTML] Polyunsaturated fatty acids, membrane organization, T cells, and antigen presentation

SR Shaikh, M Edidin - The American journal of clinical nutrition, 2006 - Elsevier
Dietary supplementation with polyunsaturated fatty acids (PUFAs), especially those of the n−
3 class, has immunosuppressive effects on both innate and adaptive immunity through …

Order from disorder, corralling cholesterol with chaotic lipids: The role of polyunsaturated lipids in membrane raft formation

SR Wassall, MR Brzustowicz, SR Shaikh… - Chemistry and physics …, 2004 - Elsevier
A myriad of health benefits including the prevention of cancer and heart disease
accompanies consumption of polyunsaturated fatty acids (PUFA). Of special importance is …