Fatty acid and peptide profiles in plasma membrane and membrane rafts of PUFA supplemented RAW264. 7 macrophages

J Schumann, A Leichtle, J Thiery, H Fuhrmann - PloS one, 2011 - journals.plos.org
The eukaryotic cell membrane possesses numerous complex functions, which are essential
for life. At this, the composition and the structure of the lipid bilayer are of particular …

Roles of polyunsaturated fatty acids, from mediators to membranes

T Harayama, T Shimizu - Journal of lipid research, 2020 - ASBMB
PUFAs, such as AA and DHA, are recognized as important biomolecules, but understanding
their precise roles and modes of action remains challenging. PUFAs are precursors for a …

Docosahexaenoic acid selectively inhibits plasma membrane targeting of lipidated proteins

J Seo, R Barhoumi, AE Johnson, JR Lupton… - The FASEB …, 2006 - Wiley Online Library
Membrane localization of lipidated cytosolic signaling proteins is mediated by interactions
between specific lipid anchors and membranes, but little is known about the regulatory role …

Regulatory activity of polyunsaturated fatty acids in T-cell signaling

W Kim, NA Khan, DN McMurray, IA Prior, N Wang… - Progress in lipid …, 2010 - Elsevier
n− 3 Polyunsaturated fatty acids (PUFA) are considered to be authentic immunosuppressors
and appear to exert beneficial effects with respect to certain immune-mediated diseases. In …

Polyunsaturated fatty acids: biochemical, nutritional and epigenetic properties

P Benatti, G Peluso, R Nicolai… - Journal of the American …, 2004 - Taylor & Francis
Dietary polyunsaturated fatty acids (PUFA) have effects on diverse physiological processes
impacting normal health and chronic diseases, such as the regulation of plasma lipid levels …

Polyunsaturated eicosapentaenoic acid displaces proteins from membrane rafts by altering raft lipid composition

TM Stulnig, J Huber, N Leitinger, EM Imre… - Journal of Biological …, 2001 - ASBMB
Polyunsaturated fatty acids (PUFAs) such as eicosapentaenoic acid (20: 5 (n-3)) inhibit T
lymphocyte activation probably by displacing acylated signaling proteins from membrane …

The biochemistry of n-3 polyunsaturated fatty acids* 210

DB Jump - Journal of Biological Chemistry, 2002 - ASBMB
Dietary n-3 polyunsaturated fatty acids (n-3 PUFA) 1 have effects on diverse physiological
processes impacting normal health and chronic disease, such as the regulation of plasma …

Dietary fats and membrane function: implications for metabolism and disease

AJ Hulbert, N Turner, LH Storlien, PL Else - Biological Reviews, 2005 - Wiley Online Library
Lipids play varied and critical roles in metabolism, with function dramatically modulated by
the individual fatty acid moities in complex lipid entities. In particular, the fatty acid …

[HTML][HTML] Docosahexaenoic acid modifies the clustering and size of lipid rafts and the lateral organization and surface expression of MHC class I of EL4 cells

SR Shaikh, BD Rockett, K Carraway - The Journal of nutrition, 2009 - Elsevier
An emerging molecular mechanism by which docosahexaenoic acid (DHA) exerts its effects
is modification of lipid raft organization. The biophysical model, based on studies with …

Do eicosapentaenoic acid and docosahexaenoic acid have the potential to compete against each other?

A Pal, AH Metherel, L Fiabane, N Buddenbaum… - Nutrients, 2020 - mdpi.com
Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are n-3 polyunsaturated
fatty acids (PUFAs) consumed in low abundance in the Western diet. Increased consumption …