Omega-3 fatty acids, lipid rafts, and T cell signaling

TY Hou, DN McMurray, RS Chapkin - European journal of pharmacology, 2016 - Elsevier
Abstract n-3 polyunsaturated fatty acids (PUFA) have been shown in many clinical studies to
attenuate inflammatory responses. Although inflammatory responses are orchestrated by a …

Mechanisms by which docosahexaenoic acid and related fatty acids reduce colon cancer risk and inflammatory disorders of the intestine

RS Chapkin, J Seo, DN McMurray, JR Lupton - Chemistry and physics of …, 2008 - Elsevier
A growing body of epidemiological, clinical, and experimental evidence has underscored
both the pharmacological potential and the nutritional value of dietary fish oil enriched in …

Dietary fats and membrane function: implications for metabolism and disease

AJ Hulbert, N Turner, LH Storlien, PL Else - Biological Reviews, 2005 - Wiley Online Library
Lipids play varied and critical roles in metabolism, with function dramatically modulated by
the individual fatty acid moities in complex lipid entities. In particular, the fatty acid …

[HTML][HTML] Docosahexaenoic acid modifies the clustering and size of lipid rafts and the lateral organization and surface expression of MHC class I of EL4 cells

SR Shaikh, BD Rockett, K Carraway - The Journal of nutrition, 2009 - Elsevier
An emerging molecular mechanism by which docosahexaenoic acid (DHA) exerts its effects
is modification of lipid raft organization. The biophysical model, based on studies with …

Do eicosapentaenoic acid and docosahexaenoic acid have the potential to compete against each other?

A Pal, AH Metherel, L Fiabane, N Buddenbaum… - Nutrients, 2020 - mdpi.com
Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are n-3 polyunsaturated
fatty acids (PUFAs) consumed in low abundance in the Western diet. Increased consumption …

Distinguishing health benefits of eicosapentaenoic and docosahexaenoic acids

FD Russell, CS Bürgin-Maunder - Marine drugs, 2012 - mdpi.com
Long chain omega-3 polyunsaturated fatty acids (LC n-3 PUFAs) are recommended for
management of patients with wide-ranging chronic diseases, including coronary heart …

Docosahexaenoic acid enhances segregation of lipids between raft and nonraft domains: 2H-NMR study

SP Soni, DS LoCascio, Y Liu, JA Williams, R Bittman… - Biophysical journal, 2008 - cell.com
Solid-state 2 H-NMR of [2 H 31]-N-palmitoylsphingomyelin ([2 H 31] 16: 0SM, PSM*),
supplemented by differential scanning calorimetry, was used for the first time, to our …

Inflammation and cardiovascular disease: are marine phospholipids the answer?

R Lordan, S Redfern, A Tsoupras, I Zabetakis - Food & function, 2020 - pubs.rsc.org
Since the discovery that Greenlandic Innuits had a lower risk of developing cardiovascular
diseases (CVD) due to their diet of fish and as a consequence high polyunsaturated fatty …

Polyunsaturated fatty acid–phospholipid remodeling and inflammation

PP Robichaud, ME Surette - Current Opinion in Endocrinology …, 2015 - journals.lww.com
Polyunsaturated fatty acid–phospholipid remodeling and infla... : Current Opinion in Endocrinology,
Diabetes and Obesity Polyunsaturated fatty acid–phospholipid remodeling and inflammation …

Metabolism and functions of docosahexaenoic acid‐containing membrane glycerophospholipids

D Hishikawa, WJ Valentine, Y Iizuka‐Hishikawa… - FEBS …, 2017 - Wiley Online Library
Omega‐3 (ω‐3) fatty acids (FA s) such as docosahexaenoic acid (DHA) and
eicosapentaenoic acid (EPA) are known to have important roles in human health and …