Polyunsaturated fatty acids and membrane organization: elucidating mechanisms to balance immunotherapy and susceptibility to infection
SR Shaikh, M Edidin - Chemistry and Physics of Lipids, 2008 - Elsevier
Polyunsaturated fatty acids (PUFAs), notably of the n-3 series, have immunosuppressive
effects which make these molecules candidates for treating inflammatory symptoms …
effects which make these molecules candidates for treating inflammatory symptoms …
Polyunsaturated fatty acids, membrane function and metabolic diseases such as diabetes and obesity
LH Storlien, AJ Hulbert, PL Else - Current Opinion in Clinical …, 1998 - journals.lww.com
Lipids play an extraordinary range of roles in normal and deranged metabolism. In diabetes
and obesity, lipids have often been seen just as impacting on the energy balance equation …
and obesity, lipids have often been seen just as impacting on the energy balance equation …
[HTML][HTML] DHA modifies the size and composition of raftlike domains: a solid-state 2H NMR study
JJ Kinnun, R Bittman, SR Shaikh, SR Wassall - Biophysical journal, 2018 - cell.com
Docosahexaenoic acid is an omega-3 polyunsaturated fatty acid that relieves the symptoms
of a wide variety of chronic inflammatory disorders. The structural mechanism is not yet …
of a wide variety of chronic inflammatory disorders. The structural mechanism is not yet …
[HTML][HTML] Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport
T Hashidate-Yoshida, T Harayama, D Hishikawa… - Elife, 2015 - elifesciences.org
Polyunsaturated fatty acids (PUFAs) in phospholipids affect the physical properties of
membranes, but it is unclear which biological processes are influenced by their regulation …
membranes, but it is unclear which biological processes are influenced by their regulation …
The nutritional and clinical significance of lipid rafts
P Yaqoob, SR Shaikh - Current Opinion in Clinical Nutrition & …, 2010 - journals.lww.com
In-vitro and animal studies show that n-3 PUFAs, cholesterol, and gangliosides modulate the
structure and composition of lipid rafts, potentially influencing a wide range of biological …
structure and composition of lipid rafts, potentially influencing a wide range of biological …
Omega 3-fatty acids: health benefits and cellular mechanisms of action
RA Siddiqui, SR Shaikh, LA Sech… - Mini reviews in …, 2004 - ingentaconnect.com
Epidemiological evidence has established that ingestion of long-chain polyunsaturated
omega-3 fatty acids (ω-3 PUFAs), abundant in fish oils, have profound effects on many …
omega-3 fatty acids (ω-3 PUFAs), abundant in fish oils, have profound effects on many …
[HTML][HTML] n-3 polyunsaturated fatty acids suppress CD4+ T cell proliferation by altering phosphatidylinositol-(4, 5)-bisphosphate [PI (4, 5) P2] organization
The mechanisms by which n-3 polyunsaturated fatty acids (n-3 PUFA), abundant in fish oil,
exert their anti-inflammatory effects have not been rigorously defined. We have previously …
exert their anti-inflammatory effects have not been rigorously defined. We have previously …
Eicosapentaenoic acid and docosahexaenoic acid regulate modified LDL uptake and macropinocytosis in human macrophages
JE McLaren, DR Michael, IA Guschina, JL Harwood… - Lipids, 2011 - Springer
There is evidence that long chain n-3 PUFA (such as from fish oils) provide atheroprotection
through, in part, changes in macrophage function although it has not been fully determined …
through, in part, changes in macrophage function although it has not been fully determined …
Omega-3 fatty acids, membrane remodeling and cancer prevention
Proteins are often credited as the macromolecule responsible for performing critical cellular
functions, however lipids have recently garnered more attention as our understanding of …
functions, however lipids have recently garnered more attention as our understanding of …
Sea cucumber and blue mussel: new sources of phospholipid enriched omega-3 fatty acids with a potential role in 3T3-L1 adipocyte metabolism
Omega (n)-3 polyunsaturated fatty acids (PUFA), namely docosahexaenoic acid (DHA) and
eicosapentaenoic acid (EPA), are known to reduce the risk of insulin resistance and …
eicosapentaenoic acid (EPA), are known to reduce the risk of insulin resistance and …