[HTML][HTML] Oleic and docosahexaenoic acid differentially phase separate from lipid raft molecules: a comparative NMR, DSC, AFM, and detergent extraction study

SR Shaikh, AC Dumaual, A Castillo, D LoCascio… - Biophysical journal, 2004 - cell.com
We have previously suggested that the ω-3 polyunsaturated fatty acid, docosahexaenoic
acid (DHA) may in part function by enhancing membrane lipid phase separation into lipid …

N-3 polyunsaturated fatty acids regulate lipid metabolism through several inflammation mediators: mechanisms and implications for obesity prevention

CC Tai, ST Ding - The Journal of nutritional biochemistry, 2010 - Elsevier
Obesity is a growing problem that threatens the health and welfare of a large proportion of
the human population. The n-3 polyunsaturated fatty acids (PUFA) are dietary factors that …

Dietary fatty acids and membrane protein function

MG Murphy - The Journal of nutritional biochemistry, 1990 - Elsevier
In recent years, there has been growing public awareness of the potential health benefits of
dietary fatty acids, and of the distinction between the effects of the ω6 and ω3 …

Hepatic levels of DHA-containing phospholipids instruct SREBP1-mediated synthesis and systemic delivery of polyunsaturated fatty acids

D Hishikawa, K Yanagida, K Nagata, A Kanatani… - Iscience, 2020 - cell.com
Polyunsaturated fatty acids (PUFAs), such as docosahexaenoic acid (DHA) and arachidonic
acid (ARA), play fundamental roles in mammalian physiology. Although PUFA imbalance …

n−3 polyunsaturated fatty acids suppress phosphatidylinositol 4,5-bisphosphate-dependent actin remodelling during CD4+ T-cell activation

TY Hou, JM Monk, YY Fan, R Barhoumi… - Biochemical …, 2012 - portlandpress.com
n− 3 PUFA (polyunsaturated fatty acids), ie DHA (docosahexaenoic acid), found in fish oil,
exhibit anti-inflammatory properties; however, the molecular mechanisms remain unclear …

n-3 PUFA: bioavailability and modulation of adipose tissue function: Symposium on 'Frontiers in adipose tissue biology'

J Kopecky, M Rossmeisl, P Flachs, O Kuda… - Proceedings of the …, 2009 - cambridge.org
Adipose tissue has a key role in the development of metabolic syndrome (MS), which
includes obesity, type 2 diabetes, dyslipidaemia, hypertension and other disorders. Systemic …

Docosahexaenoic acid affects cell signaling by altering lipid rafts

W Stillwell, SR Shaikh, M Zerouga… - Reproduction …, 2005 - rnd.edpsciences.org
With 22 carbons and 6 double bonds docosahexaenoic acid (DHA) is the longest and most
unsaturated fatty acid commonly found in membranes. It represents the extreme example of …

From fat to fat-1: a tale of omega-3 fatty acids

JX Kang - The Journal of membrane biology, 2005 - Springer
Omega-3 (or n-3) fatty acids are fats found within foods and body tissues. They are unique
because of the following characteristics: Structurally they appear as a long hydrocarbon …

[HTML][HTML] Mechanisms of action of (n-3) fatty acids

PC Calder - The Journal of nutrition, 2012 - Elsevier
Abstract (n-3) PUFA are a family of biologically active fatty acids. The simplest member of
this family, a-linolenic acid, can be converted to the more biologically active very long-chain …

[HTML][HTML] Perspective: the saturated fat–unsaturated oil dilemma: relations of dietary fatty acids and serum cholesterol, atherosclerosis, inflammation, cancer, and all …

GD Lawrence - Advances in Nutrition, 2021 - Elsevier
PUFAs are known to regulate cholesterol synthesis and cellular uptake by multiple
mechanisms that do not involve SFAs. Polymorphisms in any of the numerous proteins …