Modulation of immune function by dietary fatty acids

EA Miles, PC Calder - Proceedings of the Nutrition Society, 1998 - cambridge.org
All mammals can synthesize fatty acids de novo from acetyl-CoA. The endproduct of the fatty
acid synthetase (EC 2.3. 1.85) enzymeispalmiticacid (l6: 0), whichinturncanbe elongated to …

Health benefits of dietary marine DHA/EPA-enriched glycerophospholipids

TT Zhang, J Xu, YM Wang, CH Xue - Progress in lipid research, 2019 - Elsevier
A typical feature of marine foods is that they are rich in docosahexaenoic acid (DHA) and
eicosapentaenoic acid (EPA), which have formed a large-scale global industry. DHA/EPA …

Lysophosphatidylcholine acyltransferase 1 protects against cytotoxicity induced by polyunsaturated fatty acids

S Akagi, N Kono, H Ariyama, H Shindou… - The FASEB …, 2016 - Wiley Online Library
The degree of fatty acid unsaturation in membrane phospholipids affects many membrane‐
associated functions and can be influenced by dietary consumption of fatty acids such as …

Effects of unsaturated fatty acids and triacylglycerols on phosphatidylethanolamine membrane structure

J Prades, SS Funari, PV Escribá, F Barceló - Journal of lipid research, 2003 - ASBMB
Lipid intake in diet regulates the membrane lipid composition, which in turn controls
activities of membrane proteins. There is evidence that fatty acids (FAs) and triacylglycerols …

[HTML][HTML] Partitioning of liquid-ordered/liquid-disordered membrane microdomains induced by the fluidifying effect of 2-hydroxylated fatty acid derivatives

M Ibarguren, DJ López, JA Encinar… - … et Biophysica Acta (BBA …, 2013 - Elsevier
Cellular functions are usually associated with the activity of proteins and nucleic acids.
Recent studies have shown that lipids modulate the localization and activity of key …

Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness

KR Levental, E Malmberg, JL Symons, YY Fan… - Nature …, 2020 - nature.com
Proper membrane physiology requires maintenance of biophysical properties, which must
be buffered from external perturbations. While homeostatic adaptation of membrane fluidity …

[HTML][HTML] Modification of membrane lipid compositions in single-celled organisms–From basics to applications

H Pichler, A Emmerstorfer-Augustin - Methods, 2018 - Elsevier
All intact cells, and their organelles, are surrounded by a∼ 30 Å hydrophobic film that
typically separates the interior from the environment. This film is composed of lipid bilayers …

Fish oil increases raft size and membrane order of B cells accompanied by differential effects on function

BD Rockett, H Teague, M Harris, M Melton… - Journal of lipid …, 2012 - ASBMB
Fish oil (FO) targets lipid microdomain organization to suppress T-cell and macrophage
function; however, little is known about this relationship with B cells, especially at the animal …

Saturated fatty acids alter the late secretory pathway by modulating membrane properties

LA Payet, L Pineau, ECR Snyder, J Colas, A Moussa… - Traffic, 2013 - Wiley Online Library
Saturated fatty acids (SFA) have been reported to alter organelle integrity and function in
many cell types, including muscle and pancreatic β‐cells, adipocytes, hepatocytes and …

Comparison of Cis and Trans Fatty Acid Containing Phosphatidylcholines on Membrane Properties

C Roach, SE Feller, JA Ward, SR Shaikh… - Biochemistry, 2004 - ACS Publications
The ever-increasing amount of trans fatty acids in the human diet has been linked to a
variety of afflictions, most notably coronary heart disease and arteriosclerosis. The …