Dietary omega-3 polyunsaturated fatty acids alter the fatty acid composition of hepatic and plasma bioactive lipids in C57BL/6 mice: a lipidomic approach

KA Balogun, CJ Albert, DA Ford, RJ Brown… - PloS one, 2013 - journals.plos.org
Background Omega (n)-3 polyunsaturated fatty acids (PUFA) are converted to bioactive lipid
components that are important mediators in metabolic and physiological pathways; …

Omega-3 fatty acid supplementation and cardiovascular disease: thematic review series: new lipid and lipoprotein targets for the treatment of cardiometabolic …

DB Jump, CM Depner, S Tripathy - Journal of lipid research, 2012 - ASBMB
Epidemiological studies on Greenland Inuits in the 1970s and subsequent human studies
have established an inverse relationship between the ingestion of omega-3 fatty acids [C 20 …

The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment …

I Johansson, VT Monsen, K Pettersen, J Mildenberger… - Autophagy, 2015 - Taylor & Francis
Accumulation and aggregation of misfolded proteins is a hallmark of several diseases
collectively known as proteinopathies. Autophagy has a cytoprotective role in diseases …

Omega‐3 polyunsaturated fatty acids and human health outcomes

PC Calder, P Yaqoob - Biofactors, 2009 - Wiley Online Library
Current intakes of very long chain ω‐3 fatty acids, eicosapentaenoic acid (EPA), and
docosahexaenoic acid (DHA) are low in most individuals living in Western countries. A good …

Docosahexaenoic acid changes lipid composition and interleukin-2 receptor signaling in membrane rafts

Q Li, M Wang, L Tan, C Wang, J Ma, N Li, Y Li… - Journal of lipid …, 2005 - ASBMB
Polyunsaturated fatty acids, including docosahexaenoic acid (DHA, 22: 6n-3), modulate
immune responses and exert beneficial immunosuppressive effects, but the molecular …

[PDF][PDF] Algae-derived polyunsaturated fatty acids: implications for human health

R Robertson, F Guihéneuf, M Schmid… - … fatty acids: sources …, 2013 - researchgate.net
Polyunsaturated fatty acids (PUFA) have been shown to exert a multitude of beneficial
health effects. Growing evidence suggests that dietary omega-3 PUFA, which are abundant …

Lipid rafts—composition, characterization, and controversies

PC Calder, P Yaqoob - The Journal of nutrition, 2007 - jn.nutrition.org
In this issue of The Journal of Nutrition, an article reporting on the effect of (n-3) PUFA on the
composition of lipid rafts in tumor cells is published, to our knowledge, for the first time (1) …

Omega-3 fatty acids in obesity and metabolic syndrome: a mechanistic update

K Albracht-Schulte, NS Kalupahana… - The Journal of nutritional …, 2018 - Elsevier
Strategies to reduce obesity have become public health priorities as the prevalence of
obesity has risen in the United States and around the world. While the anti-inflammatory and …

Nutrigenomics of ω-3 fatty acids: Regulators of the master transcription factors

M Rodríguez-Cruz, DS Serna - Nutrition, 2017 - Elsevier
It is well known that ω-3 long-chain polyunsaturated fatty acids (LC-PUFAs) control some
key molecular cell mechanisms, resulting in a beneficial role in inflammatory diseases. Such …

Omega-3 fatty acids in cellular membranes: a unified concept

RC Valentine, DL Valentine - Progress in lipid research, 2004 - Elsevier
The Omega-3 fatty acid DHA (docosahexaenoic acid, 22: 6) and its sister molecule EPA
(eicosapentaenoic acid, 20: 5) are highlighted here. These highly unsaturated fatty acids are …