Emerging roles of mesenchymal stem/stromal-cell-derived extracellular vesicles in cancer therapy

A Nicodemou, S Bernátová, M Čeháková, Ľ Danišovič - Pharmaceutics, 2023 - mdpi.com
Despite the tremendous efforts of many researchers and clinicians, cancer remains the
second leading cause of mortality worldwide. Mesenchymal stem/stromal cells (MSCs) are …

Mesenchymal stem cell‐derived extracellular vesicles: Roles in tumor growth, progression, and drug resistance

X Zhang, H Tu, Y Yang, L Fang, Q Wu… - Stem Cells …, 2017 - Wiley Online Library
Mesenchymal stem cells (MSCs) are ubiquitously present in many tissues. Due to their
unique advantages, MSCs have been widely employed in clinical studies. Emerging …

Therapeutic roles of mesenchymal stem cell-derived extracellular vesicles in cancer

Z Weng, B Zhang, C Wu, F Yu, B Han, B Li… - Journal of hematology & …, 2021 - Springer
Extracellular vesicles (EVs) are cell-derived membrane structures enclosing proteins, lipids,
RNAs, metabolites, growth factors, and cytokines. EVs have emerged as essential …

Mesenchymal stem/stromal cell-derived extracellular vesicles and their potential as novel immunomodulatory therapeutic agents

V Börger, M Bremer, R Ferrer-Tur, L Gockeln… - International journal of …, 2017 - mdpi.com
Extracellular vesicles (EVs), such as exosomes and microvesicles, have been identified as
mediators of a newly-discovered intercellular communication system. They are essential …

Mesenchymal stromal cell-derived extracellular vesicles as biological carriers for drug delivery in cancer therapy

MC Sanmartin, FR Borzone, MB Giorello… - … in Bioengineering and …, 2022 - frontiersin.org
Cancer is the second leading cause of death worldwide, with 10.0 million cancer deaths in
2020. Despite advances in targeted therapies, some pharmacological drawbacks …

Mesenchymal stem cell-derived extracellular vesicles: toward cell-free therapeutic applications

S Rani, AE Ryan, MD Griffin, T Ritter - Molecular Therapy, 2015 - cell.com
Mesenchymal stem (stromal) cells (MSCs) are multipotent cells with the ability to differentiate
into several cell types, thus serving as a cell reservoir for regenerative medicine. Much of the …

MSC-derived extracellular vesicles in tumors and therapy

T Luo, J von der Ohe, R Hass - Cancers, 2021 - mdpi.com
Simple Summary Therapeutic functions of mesenchymal stroma-/stem-like cells (MSCs) are
mediated predominantly through paracrine effects by the release of various different …

[HTML][HTML] The potential roles of stem cell-derived extracellular vesicles as a therapeutic tool

YC Huang, LC Lai - Annals of Translational Medicine, 2019 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) of mesenchymal stem cells (MSCs) are secreted by live cells
and possess the same regenerative potential and immunomodulatory ability as their …

[HTML][HTML] Role of mesenchymal stromal cell-derived extracellular vesicles in tumour microenvironment

A Adamo, G Dal Collo, R Bazzoni… - Biochimica et Biophysica …, 2019 - Elsevier
Stromal cells, deriving from mesenchymal stromal cells (MSCs), are crucial component of
tumour microenvironment and represent key regulators of tumour processes. MSCs can be …

[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles in Cancer Therapy Resistance: from Biology to Clinical Opportunity

C Shan, Y Liang, K Wang, P Li - International Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are a type of stromal cells characterized by their properties
of self-renewal and multi-lineage differentiation, which make them prominent in regenerative …