Meiotic nondisjunction and resulting aneuploidy can lead to severe health consequences in
humans. Aneuploidy rescue can restore euploidy but may result in uniparental disomy …

Purpose Uniparental disomy (UPD) is the rare occurrence of two homologous chromosomes
originating from the same parent and is typically identified by marker analysis or single …

Uniparental disomy (UPD) is defined as two copies of a whole chromosome derived from the
same parent. There can be multiple mechanisms that lead to UPD; these are reviewed in the …

Uniparental disomy (UPD) occurs when both homologs of a chromosomal pair come from
the father (paternal UPD) or the mother (maternal UPD). Depending on the mechanism by …

Purpose Data on the clinical prevalence and spectrum of uniparental disomy (UPD) remain
limited. Trio exome sequencing (ES) presents a comprehensive method for detection of UPD …

Uniparental disomy (UPD), the exceptional derivation of a pair of the offspring chromosomes
from one parent only, may be compatible with normal or abnormal development and can …

Uniparental disomy (UPD) refers to the situation in which both homologues of a
chromosomal region/segment have originated from only one parent. This can involve the …

OBJECTIVE To review all cases with segmental and/or complex uniparental disomy (UPD),
to study aetiology and mechanisms of formation, and to draw conclusions. DESIGN …

Mosaic aneuploidy and uniparental disomy (UPD) arise from mitotic or meiotic events. There
are differences between these mechanisms in terms of (i) impact on embryonic …

Uniparental disomy (UPD) refers to the situation in which both copies of a chromosome pair
have originated from one parent. In humans, it can result in clinical conditions by producing …