Neutrophils are short-lived cells of the innate immune system and the first line of defense at
the site of an infection and tissue injury. Pattern recognition receptors on neutrophils …

Spinal cord injuries remain a critical issue in experimental and clinical research nowadays,
and it is now well accepted that the immune response and subsequent inflammatory …

Secondary spinal cord injury is caused by an inflammatory response cascade, and the
process is irreversible. The immune system, as a mediator of inflammation, plays an …

Secondary pathogenesis following primary mechanical damage to the spinal cord is
believed to be the ultimate reason for the limitation of currently available therapies …

Inflammation is classically defined as a host defense mechanism triggered by injury or
infection whereby leukocytes and humoral factors attempt to restore homeostasis to the …

Traumatic spinal cord injury (SCI) causes irreparable severe motor and sensory dysfunction.
Mechanical trauma rapidly leads to blood-spinal cord barrier disruption, neural cell death …

The incidence of spinal cord injuries (SCI) is high every year. As the spinal cord is the
highway that allows for the brain to control the rest of the body, spinal cord injuries greatly …

Recruitment of inflammatory leukocytes to the injured spinal cord is a physiological
response that is associated with the production of cytokines and proteinases that are …

Strategies that block infiltration of leukocytes into the injured spinal cord improve sparing of
white matter and neurological recovery. In this article, we examine the dependency of …

Spinal cord injury (SCI) is a devastating neurological condition prevalent worldwide. Where
the pathological mechanisms underlying SCI are concerned, we can distinguish between …