At present no successful treatment is available for advanced thyroid cancer, which
comprises poorly differentiated, anaplastic, and metastatic or recurrent differentiated thyroid …

The incidence of thyroid cancer is growing the fastest among all cancers in the United
States, especially in women. The number of patients with thyroid neoplasm is part of an even …

An increasing body of evidence suggests that epigenetic changes (DNA methylation,
remodeling and post-translational modification of chromatin) play important roles in thyroid …

Thyroid cancer remains the highest prevailing endocrine malignancy, and its incidence rate
has progressively increased in the previous years. Above 95% of thyroid tumor are follicular …

Biologic and Clinical Perspectives on Thyroid Cancer | New England Journal of Medicine Skip to
main content The New England Journal of Medicine homepage Advanced Search SEARCH …

Gain-of-function mutations in oncogenes have aided our understanding of the molecular
mechanisms of thyroid carcinogenesis. Mutations or deletions cause inactivation of tumor …

Thyroid cancer is a common endocrine malignancy. There has been exciting progress in
understanding its molecular pathogenesis in recent years, as best exemplified by the …

Thyroid carcinoma (TC) is the most frequent malignant neoplasm of the endocrine system.
Molecular methods for diagnosis of invasive thyroid disease can be effectively adopted …

Advanced thyroid cancer refers to thyroid tumors which are resistant to conventional
therapies and do not respond to radioiodine and comprises metastatic or recurrent …

Thyroid cancer comprises different clinical and histological entities. Whereas differentiated
(DTCs) malignancies are sensitive to radioiodine therapy, anaplastic (ATCs) and medullary …