Mutation-induced changes in the receptor-binding interface of the SARS-CoV-2 Delta variant B. 1.617. 2 and implications for immune evasion
Following the initial surges of the Alpha (B. 1.1. 7) and the Beta (B. 1.351) variants, a more
infectious Delta variant (B. 1.617. 2) is now surging, further deepening the health crises …
infectious Delta variant (B. 1.617. 2) is now surging, further deepening the health crises …
[HTML][HTML] Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies
Abstract The SARS-CoV-2 Delta variant is currently the dominant circulating strain in the
world. Uncovering the structural basis of the enhanced transmission and altered immune …
world. Uncovering the structural basis of the enhanced transmission and altered immune …
[HTML][HTML] Delta variant (B. 1.617. 2) sublineages do not show increased neutralization resistance
P Arora, A Kempf, I Nehlmeier, L Graichen… - Cellular & molecular …, 2021 - nature.com
The emergence of SARS-CoV-2 variants threatens efforts to control the COVID-19
pandemic. At present, the global spread of the Delta (B. 1.617. 2) variant is responsible for a …
pandemic. At present, the global spread of the Delta (B. 1.617. 2) variant is responsible for a …
[HTML][HTML] Functional effects of receptor-binding domain mutations of SARS-CoV-2 B. 1.351 and P. 1 variants
R Bayarri-Olmos, I Jarlhelt, LB Johnsen… - Frontiers in …, 2021 - frontiersin.org
The recent identification and rise to dominance of the P. 1 and B. 1.351 SARS-CoV-2
variants have brought international concern because they may confer fitness advantages …
variants have brought international concern because they may confer fitness advantages …
In vitro data suggest that Indian delta variant B. 1.617 of SARS‐CoV‐2 escapes neutralization by both receptor affinity and immune evasion
G Augusto, MO Mohsen, S Zinkhan, X Liu, M Vogel… - Allergy, 2022 - Wiley Online Library
Background Emerged mutations can be attributed to increased transmissibility of the B.
1.617 and B. 1.36 Indian delta variants of SARS‐CoV‐2, most notably substitutions …
1.617 and B. 1.36 Indian delta variants of SARS‐CoV‐2, most notably substitutions …
[HTML][HTML] Receptor binding, immune escape, and protein stability direct the natural selection of SARS-CoV-2 variants
V Upadhyay, A Lucas, S Panja, R Miyauchi… - Journal of Biological …, 2021 - ASBMB
Emergence of new severe acute respiratory syndrome coronavirus 2 variants has raised
concerns related to the effectiveness of vaccines and antibody therapeutics developed …
concerns related to the effectiveness of vaccines and antibody therapeutics developed …
[HTML][HTML] Experimental evidence for enhanced receptor binding by rapidly spreading SARS-CoV-2 variants
C Laffeber, K de Koning, R Kanaar… - Journal of molecular …, 2021 - Elsevier
Rapidly spreading new variants of SARS-CoV-2 carry multiple mutations in the viral spike
protein which attaches to the angiotensin converting enzyme 2 (ACE2) receptor on host …
protein which attaches to the angiotensin converting enzyme 2 (ACE2) receptor on host …
Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission leads to the
emergence of variants, including the B. 1.617. 2 (Delta) variant of concern that is causing a …
emergence of variants, including the B. 1.617. 2 (Delta) variant of concern that is causing a …
[HTML][HTML] Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants continue to
emerge during the global pandemic and may facilitate escape from current antibody …
emerge during the global pandemic and may facilitate escape from current antibody …
[HTML][HTML] SARS-CoV-2 variants B. 1.351 and P. 1 escape from neutralizing antibodies
The global spread of SARS-CoV-2/COVID-19 is devastating health systems and economies
worldwide. Recombinant or vaccine-induced neutralizing antibodies are used to combat the …
worldwide. Recombinant or vaccine-induced neutralizing antibodies are used to combat the …
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