Omega-3 polyunsaturated fatty acids for major depressive disorder

KP Su, SM Wang, CU Pae - Expert Opinion on Investigational …, 2013 - Taylor & Francis
Introduction: Omega-3 polyunsaturated fatty acids (omega-3 PUFAs) are not synthesized by
the human body; they must be derived from dietary sources and they have been known to be …

Role of omega-3 fatty acids in the treatment of depressive disorders: a comprehensive meta-analysis of randomized clinical trials

G Grosso, A Pajak, S Marventano, S Castellano… - PloS one, 2014 - journals.plos.org
Background Despite omega-3 polyunsaturated fatty acids (PUFA) supplementation in
depressed patients have been suggested to improve depressive symptomatology, previous …

[PDF][PDF] The role of omega-3 fatty acids in mood disorders

LA Stahl, DP Begg, RS Weisinger… - Current Opinion in …, 2008 - researchgate.net
Research has established that docosahexaenoic acid (DHA), a long-chain omega-3
polyunsaturated fatty acid (PUFA), plays a fundamental role in brain structure and function …

N-3 (omega-3) polyunsaturated Fatty acids in the pathophysiology and treatment of depression: pre-clinical evidence

B Levant - CNS & Neurological Disorders-Drug Targets …, 2013 - ingentaconnect.com
A growing literature suggests the association of low tissue levels and/or dietary intake of n-
polyunsaturated fatty acids (PUFA) with depressive illnesses. Animal studies show that low …

Omega-3 fatty acids in major depressive disorder: a preliminary double-blind, placebo-controlled trial

KP Su, SY Huang, CC Chiu, WW Shen - European …, 2003 - Elsevier
Patients with depression have been extensively reported to be associated with the
abnormality of omega-3 polyunsaturated fatty acids (PUFAs), including significantly low …

Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for major depressive disorder

RJT Mocking, I Harmsen, J Assies, MWJ Koeter… - Translational …, 2016 - nature.com
Omega-3 polyunsaturated fatty acid (PUFA) supplementation has been proposed as
(adjuvant) treatment for major depressive disorder (MDD). In the present meta-analysis, we …

Omega 3 polyunsaturated fatty acids and the treatment of depression

G Deacon, C Kettle, D Hayes, C Dennis… - Critical reviews in food …, 2017 - Taylor & Francis
Depression is a common, recurrent, and debilitating illness that has become more prevalent
over the past 100 years. This report reviews the etiology and pathophysiology of depression …

A multi-national, multi-disciplinary Delphi consensus study on using omega-3 polyunsaturated fatty acids (n-3 PUFAs) for the treatment of major depressive disorder

TW Guu, D Mischoulon, J Sarris, J Hibbeln… - Journal of affective …, 2020 - Elsevier
Introduction Omega-3 polyunsaturated fatty acids (n-3 PUFAs) are recommended as an
integrative treatment for major depressive disorder (MDD). In 2019, the International Society …

Omega‐3 fatty acids for depression in adults

KM Appleton, PD Voyias, HM Sallis… - Cochrane Database …, 2021 - cochranelibrary.com
Background Major depressive disorder (MDD) is highly debilitating, difficult to treat, has a
high rate of recurrence, and negatively impacts the individual and society as a whole. One …

Omega-3 polyunsaturated fatty acids and reduction of depressive symptoms in older adults: a systematic review and meta-analysis

ZG Bai, A Bo, SJ Wu, QY Gai, I Chi - Journal of affective disorders, 2018 - Elsevier
Objective The aim of this study is to systematically review the efficacy of omega-3
polyunsaturated fatty acid (n-3 PUFA) supplements in reducing depressive symptoms …