Overexpression of soluble urokinase receptor (suPAR) causes pathology in animal models
similar to primary FSGS, and one recent study demonstrated elevated levels of serum …

Results This study examined 110 samples retrieved from 99 individuals (between January
2011 and April 2012), aged 1–21 years; of these individuals, 20 had primary FSGS, 24 had …

Background Recently, serum soluble urokinase receptor (suPAR) has been proposed as a
cause of two thirds of cases of focal segmental glomerulosclerosis (FSGS). It was noted to …

The soluble urokinase receptor (suPAR) promotes proteinuria and induces focal segmental
glomerulosclerosis (FSGS)-like lesions in mice. A serum suPAR concentration cutoff of 3000 …

Circulating levels of soluble forms of urokinase-type plasminogen activator receptor (suPAR)
are generally elevated in sera from children and adults with FSGS compared with levels in …

It has been suggested that soluble urokinase receptor (suPAR) is a causative circulating
factor for and a biomarker of focal and segmental glomerulosclerosis (FSGS). Here we …

Focal segmental glomerulosclerosis (FSGS) is one of the primary glomerular disorders in
both children and adults which can progress to end‐stage renal failure. Although there are …

In this prospective study, we measured serum levels of the soluble urokinase receptor
(suPAR) in pediatric patients with nephrotic syndrome of various etiologies. Mean levels of …

Elevated serum-soluble urokinase receptor (suPAR) levels have been described in patients
with focal segmental glomerulosclerosis (FSGS) in several different cohorts. However, it …

The urokinase-type plasminogen activator receptor (uPAR) has important functions in cell
migration. uPAR can be shed from the cell membrane resulting in soluble uPAR (suPAR) …