Mechanical force loading exerts important effects on the skeleton by controlling bone mass
and strength. Several in vivo experimental models evaluating the effects of mechanical …

Mechanical stress produced by orthodontic forces is a factor in the remodeling of periodontal
ligaments (PDLs) and alveolar bone. It has been reported that the expression of a number of …

Orthodontic tooth movement is achieved by mechanical loading; however, the biological
mechanism involved in this process is not clearly understood owing to the lack of a suitable …

OBJECTIVE: In orthodontic tooth movement, some cytokines released from periodontal
ligament fibroblasts and alveolar bone osteoblasts on the pressure side can alter the normal …

Nozaki K, Kaku M, Yamashita Y, Yamauchi M, Miura H. Effect of cyclic mechanical loading
on osteoclast recruitment in periodontal tissue. J Periodont Res 2009; doi: 10.1111/j. 1600 …

Compressive force during orthodontic tooth movement induces osteoclast formation in vivo.
TNF-α plays an important role in mouse osteoclast formation and bone resorption induced …

During orthodontic tooth movement, mechanical stresses induce inflammatory reactions in
the periodontal ligament (PDL). We hypothesized that chemokines released from PDL cells …

Aim This study aimed to evaluate the contribution of biomechanical loading to inflammation‐
induced tissue destruction. Materials and Methods A total of 144 adult Holtzman rats were …

Orthodontic force‐induced stresses cause dynamic alterations within the extracellular matrix
and within the cytoskeleton of cells in the periodontal ligament and alveolar bone, mediating …

Objectives Mechanical loading is a potential activator of inflammation and able to stimulate
factors for periodontal and alveolar bone destruction. Aim of this study was to investigate the …