The involvement of the transcription factor c-Myb in promoting the proliferation and inhibition
of erythroid cell differentiation has been established in leukemia cell models. The anemia …

The c‐Myb transcription factor is expressed in immature haemopoietic cells and at key
stages during differentiation. Loss of the c‐myb gene results in embryonic lethality because …

A full-length human c-myb cDNA clone has been isolated from a CCRF-CEM leukemia cell
cDNA library. The plasmid vector contains simian virus 40-derived promotor, splice, and …

The nuclear proto-oncogene c-myb plays crucial roles in the growth, survival, and
differentiation of hematopoietic cells. We established three lines of erythropoietin receptor …

The transcription factor c-myb has emerged as one of the key regulators of vertebrate
hematopoiesis. In mice, it is dispensable for primitive stages of blood cell development but …

While it has long been known that the transcription factor c-Myb is an essential regulator of
hematopoiesis, its precise molecular targets have remained elusive. Cell line studies …

The c-myb gene encodes a sequence specific transactivator that is required for fetal
hematopoiesis, but its potential role in other tissues is less clear because of the early fetal …

The c-myb transcription factor is highly expressed in immature hematopoietic cells and down-
regulated during differentiation. To define its role during the hematopoietic lineage …

The definitive hematopoietic cell lineages have been proposed to originate from hemogenic
endothelial cells during mouse embryogenesis. c-Myb is a transcription factor that is …

The c-myb proto-oncogene encodes a sequence-specific DNA-binding protein. To better
understand its normal biological function, we have altered the c-myb gene by homologous …