Transcription factors are key regulatory proteins in all living beings. In fungi, transcription
factors include either broad-domain regulatory proteins that affect the expression of many …

The most commonly used β-lactam antibiotics for the therapy of infectious diseases are
penicillin and cephalosporin. Penicillin is produced as an end product by some fungi, most …

In 2004, the protein LaeA was identified and characterized as a global regulator of
secondary metabolism in the fungus Aspergillus nidulans. Since this initial report, LaeA has …

Filamentous fungi produce a number of small bioactive molecules as part of their secondary
metabolism ranging from benign antibiotics such as penicillin to threatening mycotoxins …

The growing demand for biofuels such as bioethanol has led to the need for identifying
alternative feedstock instead of conventional substrates like molasses, etc. Lignocellulosic …

Fungal secondary metabolism and morphological development have been shown to be
intimately associated at the genetic level. Much of the literature has focused on the co …

LaeA was first identified as a novel Aspergillus nuclear protein which functions as a global
regulator of secondary metabolism, morphogenetic development, and antibiotic production …

Sensing and responding to environmental cues is critical to the lifestyle of filamentous fungi.
How environmental variation influences fungi to produce a wide diversity of ecologically …

In filamentous fungal Aspergillus species, growth, development, and secondary metabolism
are genetically programmed biological processes, which require precise coordination of …

Fungal secondary metabolites play multiple biological roles in development, virulence,
defense, adaptation, and stress response. Many of these low-molecular-mass compounds …