The endothelial cell (EC) lining of the pulmonary vasculature forms a semipermeable barrier
between the blood and the interstitium of the lung. Disruption of this barrier occurs during …

Endothelial cells (EC) form a semi-permeable barrier between the interior space of blood
vessels and the underlying tissues. In acute lung injury (ALI) the EC barrier is weakened …

Actomyosin contraction directly regulates endothelial cell (EC) permeability, but intracellular
redistribution of cytoskeletal tension associated with EC permeability is poorly understood …

Hemodynamic forces in the form of shear stress (SS) and mechanical strain imposed by
circulating blood are recognized factors involved in the control of systemic endothelial cell …

The biomechanical properties of connective tissues play fundamental roles in how
mechanical interactions of the body with its environment produce physical forces at the …

Circulating barrier disruptive agonists bind specific cell membrane receptors and trigger
signal transduction pathways leading to the activation of cell contractility and endothelial cell …

Mechanical forces affect both the function and phenotype of cells in the lung. In this
symposium, recent studies were presented that examined several aspects of biomechanics …

Thrombin-induced barrier dysfunction of pulmonary endothelial monolayer is associated
with dramatic cytoskeletal reorganization, activation of actomyosin contraction, and gap …

Epithelial cells of the lung are located at the interface between the environment and the
organism and serve many important functions including barrier protection, fluid balance …

Mechanical stress plays a critical role among development, functional maturation, and
pathogenesis of pulmonary tissues, especially for the alveolar epithelial cells and vascular …