[HTML][HTML] The Effects of Titanium Dioxide Nanoparticles on Osteoblasts Mineralization: A Comparison between 2D and 3D Cell Culture Models

G de Souza Castro, W de Souza, TSM Lima… - Nanomaterials, 2023 - mdpi.com
Although several studies assess the biological effects of micro and titanium dioxide
nanoparticles (TiO2 NPs), the literature shows controversial results regarding their effect on …

Evaluation of osteogenic potentials of titanium dioxide nanoparticles with different sizes and shapes

Y Ren, X Feng, X Lang, J Wang, Z Du… - Journal of …, 2020 - Wiley Online Library
TiO2 nanoparticles (NPs) have the potential to be used in the human body as an artificial
implant because of their special physicochemical properties. However, information about the …

[HTML][HTML] The two faces of titanium dioxide nanoparticles bio-camouflage in 3D bone spheroids

W Souza, SG Piperni, P Laviola, AL Rossi, MID Rossi… - Scientific reports, 2019 - nature.com
Titanium (Ti) and its alloys are widely used in dental implants and hip-prostheses due to
their excellent biocompatibility. Growing evidence support that surface degradation due to …

Characterization of the in Vitro Osteogenic Response to Submicron TiO2 Particles of Varying Structure and Crystallinity

CB Tovani, CR Ferreira, AMS Simao, M Bolean… - ACS …, 2020 - ACS Publications
Titanium oxide (TiO2) nano-/microparticles have been widely used in orthopedic and dental
sciences because of their excellent mechanical properties, chemical stability, and ability to …

TiO2 nanoparticles disrupt cell adhesion and the architecture of cytoskeletal networks of human osteoblast‐like cells in a size dependent manner

M Ibrahim, J Schoelermann, K Mustafa… - Journal of Biomedical …, 2018 - Wiley Online Library
Human exposure to titanium dioxide nanoparticles (nano‐TiO2) is increasing. An internal
source of nano‐TiO2 is represented by titanium‐based orthopedic and dental implants can …

[HTML][HTML] Investigating the influence of titanium particle size and concentration on osteogenic response of human osteoblasts–in vitro study

S Sheela, W Kheder, ABR Samsudin - Biomaterial Investigations in …, 2024 - ncbi.nlm.nih.gov
Purpose The purpose of this study was to investigate the correlation between the size and
concentration of titanium particles and the osteogenic response of human osteoblasts …

Influence of titanium dioxide nanorods with different surface chemistry on the differentiation of rat bone marrow mesenchymal stem cells

S Shrestha, Z Mao, Y Fedutik, C Gao - Journal of Materials Chemistry …, 2016 - pubs.rsc.org
In this study, four kinds of TiO2 nanorods (TiO2 NRs), with similar aspect ratios but different
surface functional groups, ie amines (–NH2), carboxyl groups (–COOH) and poly (ethylene …

[HTML][HTML] Nanostructured TiO2 Surfaces Promote Human Bone Marrow Mesenchymal Stem Cells Differentiation to Osteoblasts

M Vercellino, G Ceccarelli, F Cristofaro, M Balli… - Nanomaterials, 2016 - mdpi.com
Micro-and nano-patterning/modification are emerging strategies to improve surfaces
properties that may influence critically cells adherence and differentiation. Aim of this work …

Analysis of the cytotoxicity of differentially sized titanium dioxide nanoparticles in murine MC3T3-E1 preosteoblasts

Y Zhang, W Yu, X Jiang, K Lv, S Sun… - Journal of Materials …, 2011 - Springer
There is an increased use of nanophase titanium dioxide (TiO 2) in bone implants and
scaffolds. However, nano-debris is generated at the bone-biomaterial interface. Therefore …

Cell differentiation on nanoscale features of a titanium surface: effects of deposition time in NaOH solution

T Fujino, Y Taguchi, S Komasa, T Sekino… - Journal of Hard Tissue …, 2014 - jstage.jst.go.jp
The present study aimed to investigate cellular behavior on nanoscale features of a titanium
surface by controlling the deposition time in NaOH. These effects were then evaluated for …