Extracellular Vesicle microRNA Biomarkers of Late Post-sepsis Survivors

T Souza-Siqueira, RB Gritte, E Weimann… - 2023 - preprints.org
Sepsis is a life-threatening condition with high hospital mortality. Elevated mortality has also
been observed in patients after hospital discharge due to post-sepsis syndrome (PSS). The …

Diagnostic potential of plasma extracellular vesicle miR-483-3p and Let-7d-3p for sepsis

G Qiu, J Fan, G Zheng, J He, F Lin, M Ge… - Frontiers in Molecular …, 2022 - frontiersin.org
Background: microRNAs (miRNAs) from circulating extracellular vesicles (EVs) have been
reported as disease biomarkers. This study aimed to identify the diagnostic value of plasma …

Circulating extracellular vesicles are associated with the clinical outcomes of sepsis

P Li, Y Wu, AJ Goodwin, B Wolf, PV Halushka… - Frontiers in …, 2023 - frontiersin.org
Introduction Sepsis is associated with endothelial cell (EC) dysfunction, increased vascular
permeability and organ injury, which may lead to mortality, acute respiratory distress …

Prognostic implication of downregulated exosomal miRNAs in patients with sepsis: a cross-sectional study with bioinformatics analysis

B Shin, JY Lee, Y Im, H Yoo, J Park, JS Lee… - Journal of Intensive …, 2023 - Springer
Background Despite the understanding of sepsis-induced extracellular vesicles (EVs), such
as exosomes, and their role in intercellular communication during sepsis, little is known …

Dynamic expression analysis of peripheral blood derived small extracellular vesicle miRNAs in sepsis progression

X Liu, D Yu, T Li, K Zhu, Y Bi, C Wang… - Journal of Cellular …, 2024 - Wiley Online Library
Immune disorders caused by sepsis have recently drawn much attention. We sought to
dynamically monitor the expression of small extracellular vesicle (sEV) miRNAs in …

Urinary microRNAs in sepsis function as a novel prognostic marker

R Han, W Li, H Tian, Y Zhao… - Experimental and …, 2023 - spandidos-publications.com
Renal dysfunction is a common complication of sepsis. Early diagnosis and prompt
treatment of sepsis with renal insufficiency are crucial for improving patient outcomes …

Role of Extracellular microRNAs in Sepsis‐Induced Acute Lung Injury

C Xiong, X Huang, S Chen, Y Li - Journal of Immunology …, 2023 - Wiley Online Library
Acute lung injury (ALI) is a life‐threatening pathological disease characterized by the
damage of pulmonary endothelial cells and epithelial cell barriers by uncontrolled …

[HTML][HTML] Circulating plasma extracellular vesicles from septic mice induce inflammation via microRNA-and TLR7-dependent mechanisms

J Xu, Y Feng, A Jeyaram, SM Jay, L Zou… - The Journal of …, 2018 - journals.aai.org
We have previously reported that a group of host cellular microRNAs (miRNAs; miR-34a-5p,
miR-122-5p, miR-145-5p, miR-146a-5p, miR-210-3p) are released into the blood during …

[HTML][HTML] A novel role for extracellular vesicles in cytopathology and new therapeutic strategies

SC Tao, SC Guo, J Collett - BioMed Research International, 2019 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are a newly discovered way by which cells communicate with
their neighbouring cells. EVs are lipid nanovesicles that enclose proteins (membrane …

The potential of extracellular microRNAs as diagnostic biomarkers for acute pulmonary infections

SN Hermann - 2022 - mediatum.ub.tum.de
Extracellular vesicle (EV) associated microRNAs (miRNAs) are shuttled during pathological
processes. After evaluating EV isolation for analyzing EV miRNAs by next-generation …