Alkaloids extracted from Uncaria rhynchophylla demonstrate neuroprotective effects in MPTP-induced experimental parkinsonism by regulating the PI3K/Akt/mTOR …
M Zheng, M Chen, C Liu, Y Fan, D Shi - Journal of ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Alkaloids isolated from Uncaria rhynchophylla (Miq.) Miq.
ex Havil.(Rubiaceae), alkaloids (URA) have been used to treat diseases related to the …
ex Havil.(Rubiaceae), alkaloids (URA) have been used to treat diseases related to the …
Anti-neuroinflammatory effects of Eucommia ulmoides Oliv. In a Parkinson's mouse model through the regulation of p38/JNK-Fosl2 gene expression
S Fan, Q Yin, D Li, J Ma, L Li, S Chai, H Guo… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Eucommia ulmoides Oliv., a Chinese medicinal
herb called “Duzhong” from the bark of Eucommia ulmoides Oliv., has been shown to …
herb called “Duzhong” from the bark of Eucommia ulmoides Oliv., has been shown to …
[HTML][HTML] Neuroprotective effects of Eucommia ulmoides Oliv. and its bioactive constituent work via ameliorating the ubiquitin-proteasome system
H Guo, F Shi, M Li, Q Liu, B Yu, L Hu - BMC Complementary and …, 2015 - Springer
Background Parkinson's disease (PD) is a chronic neurodegenerative disorder
characterized by a loss of dopaminergic neurons in the substantia nigra, decreased striatal …
characterized by a loss of dopaminergic neurons in the substantia nigra, decreased striatal …
Aucubin alleviates glial cell activation and preserves dopaminergic neurons in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced parkinsonian mice
YL Zhu, MF Sun, XB Jia, PH Zhang, YD Xu… - …, 2018 - journals.lww.com
Aucubin (AUC) is a major bioactive ingredient in Eucommia ulmoides, Plantain asiatica, and
Aucuba japonica, and has been shown to exert anti-inflammatory, antioxidative, and …
Aucuba japonica, and has been shown to exert anti-inflammatory, antioxidative, and …
Protection by rhynchophylline against MPTP/MPP+-induced neurotoxicity via regulating PI3K/Akt pathway
M Zheng, M Chen, W Wang, M Zhou, C Liu… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Isolated from Uncaria rhynchophylla (U.
rhynchophylla), rhynchophylline (Rhy) has been applied for treating diseases related to …
rhynchophylla), rhynchophylline (Rhy) has been applied for treating diseases related to …
Neuroprotective effects of puerarin on 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine induced Parkinson's disease model in mice
G Zhu, X Wang, S Wu, X Li, Q Li - Phytotherapy Research, 2014 - Wiley Online Library
Puerarin, an active component of Pueraria montana var. lobata (Willd.) Sanjappa & Pradeep
is well‐known for its anti‐oxidative and neuroprotective activities. Although anti‐Parkinson's …
is well‐known for its anti‐oxidative and neuroprotective activities. Although anti‐Parkinson's …
Effects of the hook of Uncaria rhynchophylla on neurotoxicity in the 6-hydroxydopamine model of Parkinson's disease
JS Shim, HG Kim, MS Ju, JG Choi, SY Jeong… - Journal of …, 2009 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: While the hook of Uncaria rhynchophylla
(URH) is a traditional herb used in northeast Asia for the treatment of Parkinson's disease …
(URH) is a traditional herb used in northeast Asia for the treatment of Parkinson's disease …
[HTML][HTML] Mucuna pruriens Protects against MPTP Intoxicated Neuroinflammation in Parkinson's Disease through NF-κB/pAKT Signaling Pathways
Till date, drugs that have been used to manage Parkinson's disease (PD) have only shown
symptomatic relief with several adverse effects besides their inability to prevent …
symptomatic relief with several adverse effects besides their inability to prevent …
[HTML][HTML] Neuroprotection Against MPP+-Induced Cytotoxicity Through the Activation of PI3-K/Akt/GSK3β/MEF2D Signaling Pathway by Rhynchophylline, the Major Tetracyclic …
S Hu, S Mak, X Zuo, H Li, Y Wang, Y Han - Frontiers in pharmacology, 2018 - frontiersin.org
Rhynchophylline is a major tetracyclic oxindole alkaloid in Uncaria rhynchophylla, which
has been extensively used as traditional herb medicine for the prevention of convulsions …
has been extensively used as traditional herb medicine for the prevention of convulsions …
Antioxidant-Rich Fraction of Urtica dioica Mediated Rescue of Striatal Mito-Oxidative Damage in MPTP-Induced Behavioral, Cellular, and Neurochemical Alterations …
R Bisht, BC Joshi, AN Kalia, A Prakash - Molecular neurobiology, 2017 - Springer
Parkinson's disease (PD) having a complex and multi-factorial neuropathology includes
mainly the degeneration of the dopaminergic nigrostriatal pathway, which is a cumulative …
mainly the degeneration of the dopaminergic nigrostriatal pathway, which is a cumulative …
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