Inhibition of methylphenidate-induced gene expression in the striatum by local blockade of D1 dopamine receptors: interhemispheric effects

M Yano, JA Beverley, H Steiner - Neuroscience, 2006 - Elsevier
Psychostimulants change the function of cortico-basal ganglia circuits. Some of these effects
are mediated by altered gene regulation in projection neurons of the striatum which …

Local infusion of the (±)-α-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor antagonist 6-cyano-7-nitroquinoxaline-2, 3-dione does not block d1 …

KA Keefe, CR Gerfen - Neuroscience, 1999 - Elsevier
Administration of selective agonists of D, dopamine receptors increases immediate early
gene expression in striatal neurons, a response which is particularly robust in the dopamine …

Dopamine-mediated gene regulation in the striatum

CR Gerfen, KA Keefe, H Steiner - Advances in pharmacology, 1997 - Elsevier
Publisher Summary Dopamine receptor-mediated gene-regulation effects provide insight
into the functional role of dopamine in the striatum. To study such regulatory processes as …

Dysregulation of gene induction in corticostriatal circuits after repeated methylphenidate treatment in adolescent rats: differential effects on zif 268 and homer 1a

L Cotterly, JA Beverley, M Yano… - European Journal of …, 2007 - Wiley Online Library
Psychostimulants and other dopamine agonists produce molecular changes in neurons of
cortico–basal ganglia–cortical circuits, and such neuronal changes are implicated in …

Scopolamine augments c-fos and zif/268 messenger RNA expression induced by the full D1 dopamine receptor agonist SKF-82958 in the intact rat striatum

JQ Wang, JF McGinty - Neuroscience, 1996 - Elsevier
It is generally accepted that the widely used, partial dopamine D1 receptor agonist, SKF-
38393, does not induce immediate early gene expression in striatal projection neurons …

D1–D2 dopamine receptor synergy in striatum: effects of intrastriatal infusions of dopamine agonists and antagonists on immediate early gene expression

KA Keefe, CR Gerfen - Neuroscience, 1995 - Elsevier
Manipulations of D1-or D2-dopamine receptors have differential and selective effects on the
striatonigral and striatopallidal output pathways of the striatum, respectively. However …

Regulation of rat cortex function by D1 dopamine receptors in the striatum

H Steiner, ST Kitai - Journal of Neuroscience, 2000 - Soc Neuroscience
Interactions between the basal ganglia and the cerebral cortex are critical for normal goal-
directed behavior. In the present study, we used immediate-early genes (c-fos, zif 268) as …

Continuous treatment with the D2 dopamine receptor agonist quinpirole decreases D2 dopamine receptors, D2 dopamine receptor messenger RNA and …

JF Chen, VJ Aloyo, B Weiss - Neuroscience, 1993 - Elsevier
Dopamine-mediated behaviors and certain biochemical and molecular events associated
with these behaviors were examined following continuous infusion of the D 1 dopamine …

Repeated methylphenidate treatment in adolescent rats alters gene regulation in the striatum

CL Brandon, H Steiner - European Journal of Neuroscience, 2003 - Wiley Online Library
Methylphenidate is a psychostimulant which inhibits the dopamine transporter and produces
dopamine overflow in the striatum, similar to the effects of cocaine. Excessive dopamine …

Differential effects of clozapine and haloperidol on dopamine receptor mRNA expression in rat striatum and cortex

SP Damask, KA Bovenkerk, G de la Pena… - Molecular brain …, 1996 - Elsevier
The regulation of the dopamine (DA) receptors is of considerable interest, in part because
treatment with antipsychotic drugs is known to upregulate striatal D2-like receptors. While …