Localized elution of corticosteroids has been used in suppressing inflammation and fibrosis
associated with implantation and continuous in vivo residence of bio-medical devices …

Dexamethasone loaded PLGA microsphere/PVA hydrogel composites were investigated as
an outer drug-eluting coating for implantable devices to provide protection against the …

Background: Continuous release of dexamethasone from PLGA microsphere/PVA hydrogel
composites has been shown to suppress the inflammatory tissue reaction in response to …

A major obstacle to the development of implantable biosensors is the foreign body response
(FBR) that results from tissue trauma during implantation and the continuous presence of the …

Dexamethasone-releasing PLGA poly (lactic-co-glycolic acid) microsphere/PVA (polyvinyl
alcohol) hydrogel composite coatings have been shown to prevent the foreign body reaction …

Background: Successful performance of implantable glucose biosensors for metabolic
monitoring is dependent on tissue compatibility. Negative immunostimulatory tissue …

The purpose of this research was to develop polylactic-co-glycolic acid (PLGA)
microspheres for continuous delivery of dexamethasone for over a 1-month period, in an …

The purpose of this research effort was to evaluate in vivo a newly developed
dexamethasone/PLGA microsphere system designed to suppress the inflammatory tissue …

The application of dexamethasone releasing poly (lactic-co-glycolic acid)(PLGA)
microspheres embedded in a poly vinyl alcohol (PVA) hydrogel coatings have been …

Implantation of synthetic materials into the body elicits inflammatory host responses that limit
medical device integration and biological performance. This inflammatory cascade involves …