[HTML][HTML] The Mechanism of Diarrhetic Shellfish Poisoning Toxin Production in Prorocentrum spp.: Physiological and Molecular Perspectives

TCH Lee, FLY Fong, KC Ho, FWF Lee - Toxins, 2016 - mdpi.com
Diarrhetic shellfish poisoning (DSP) is a gastrointestinal disorder caused by the
consumption of seafood contaminated with okadaic acid (OA) and dinophysistoxins (DTXs) …

[HTML][HTML] Experimental basis for the high oral toxicity of dinophysistoxin 1: A comparative study of DSP

DA Fernández, MC Louzao, M Fraga, N Vilariño… - Toxins, 2014 - mdpi.com
Okadaic acid (OA) and its analogues, dinophysistoxin 1 (DTX1) and dinophysistoxin 2
(DTX2), are lipophilic and heat-stable marine toxins produced by dinoflagellates, which can …

Production and excretion of okadaic acid, pectenotoxin-2 and a novel dinophysistoxin from the DSP-causing marine dinoflagellate Dinophysis acuta–effects of light …

LT Nielsen, B Krock, PJ Hansen - Harmful Algae, 2013 - Elsevier
Diarrhetic shellfish poisoning (DSP) toxins constitute a severe economic threat to shellfish
industries and a major food safety issue for shellfish consumers. The prime producers of the …

The effects of the diarrhetic shellfish poisoning toxins, okadaic acid and dinophysistoxin-1, on the growth of microalgae

AJ Windust, JLC Wright, JL McLachlan - Marine biology, 1996 - Springer
The diarrhetic shellfish poisoning toxins okadaic acid (OA) and dinophysistoxin-1 (DTX-1)
are potent phosphatase inhibitors produced by certain species of marine dinoflagellates. OA …

[HTML][HTML] Effects of the marine biotoxins okadaic acid and dinophysistoxins on fish

M Corriere, L Soliño, PR Costa - Journal of Marine Science and …, 2021 - mdpi.com
Natural high proliferations of toxin-producing microorganisms in marine and freshwater
environments result in dreadful consequences at the socioeconomically and environmental …

[HTML][HTML] Comparative analysis of the cytotoxic effects of okadaic acid-group toxins on human intestinal cell lines

PJ Ferron, K Hogeveen, V Fessard, L Le Hégarat - Marine drugs, 2014 - mdpi.com
The phycotoxin, okadaic acid (OA) and dinophysistoxin 1 and 2 (DTX-1 and-2) are protein
phosphatase PP2A and PP1 inhibitors involved in diarrhetic shellfish poisoning (DSP). Data …

[HTML][HTML] Toxic Responses of Different Shellfish Species after Exposure to Prorocentrum lima, a DSP Toxins Producing Dinoflagellate

MH Ye, DW Li, QD Cai, YH Jiao, Y Liu, HY Li, WD Yang - Toxins, 2022 - mdpi.com
Prorocentrum lima is a global benthic dinoflagellate that produces diarrhetic shellfish
poisoning (DSP) toxins, which can be ingested by filter-feeding bivalves, and eventually …

Toxicity to medaka fish embryo development of okadaic acid and crude extracts of Prorocentrum dinoflagellates

N Escoffier, J Gaudin, K Mezhoud, H Huet… - Toxicon, 2007 - Elsevier
Chronic and subchronic toxicity following exposure to the DSP (Diarrhetic shellfish
poisoning) toxin okadaic acid (OA) is receiving increasing attention as a public human …

[HTML][HTML] Profiling of Extracellular Toxins Associated with Diarrhetic Shellfish Poison in Prorocentrum lima Culture Medium by High-Performance Liquid …

L Pan, J Chen, H Shen, X He, G Li, X Song, D Zhou… - Toxins, 2017 - mdpi.com
Extracellular toxins released by marine toxigenic algae into the marine environment have
attracted increasing attention in recent years. In this study, profiling, characterization and …

Comparison of a protein phosphatase inhibition assay, HPLC assay and enzyme-linked immunosorbent assay with the mouse bioassay for the detection of diarrhetic …

PE Núñez, AC Scoging - International journal of food microbiology, 1997 - Elsevier
Consumption of shellfish contaminated with algal toxins produced by marine dinoflagellates
can lead to diarrhetic shellfish poisoning (DSP). UK legislation necessitates toxin detection …