The Role of MicroRNAs in Development and Function of Regulatory T Cells–Lessons for a Better Understanding of MicroRNA Biology

H Kunze-Schumacher, A Krueger - Frontiers in immunology, 2020 - frontiersin.org
MicroRNAs (miRNAs) have emerged as critical posttranscriptional regulators of the immune
system, including function and development of regulatory T (Treg) cells. Although this critical …

MicroRNA networks in regulatory T cells

X Tang, R Tang, Y Xu, Q Wang, Y Hou, S Shen… - Journal of physiology …, 2014 - Springer
MicroRNAs (miRNAs) are small regulatory RNAs that bind directly to complementary
sequences on target messenger RNA (mRNA) transcripts, resulting in translational …

MicroRNA regulation of T-lymphocyte immunity: modulation of molecular networks responsible for T-cell activation, differentiation, and development

K Podshivalova, DR Salomon - Critical Reviews™ in …, 2013 - dl.begellhouse.com
MicroRNAs (miRNA) are a class of small non-coding RNAs that constitute an essential and
evolutionarily conserved mechanism for post-transcriptional gene regulation. Multiple …

microRNAs function in CD8+T cell biology

Y Liang, HF Pan, DQ Ye - Journal of Leucocyte Biology, 2015 - academic.oup.com
During an immune response, CD8+ T cells can differentiate into multiple types of effector
and memory cells that are important components of immune surveillance. However, their …

[HTML][HTML] MicroRNA regulation of CD8+ T cell responses

JD Gagnon, KM Ansel - Non-coding RNA investigation, 2019 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are a class of short noncoding RNAs that play critical roles in the
regulation of a broad range of biological processes. Like transcription factors, miRNAs exert …

Cell‐intrinsic and‐extrinsic roles of miRNAs in regulating T cell immunity

S Cho, J Dong, LF Lu - Immunological reviews, 2021 - Wiley Online Library
T cells are crucial to generate an effective response against numerous invading microbial
pathogens and play a pivotal role in tumor surveillance and elimination. However, unwanted …

Regulatory roles of MicroRNA in shaping T cell function, differentiation and polarization

RA Naqvi, M Datta, SH Khan, AR Naqvi - Seminars in Cell & …, 2022 - Elsevier
T lymphocytes are an integral component of adaptive immunity with pleotropic effector
functions. Impairment of T cell activity is implicated in various immune pathologies including …

microRNAs at the regulatory frontier: an investigation into how microRNAs impact the development and effector functions of CD4 T cells

EA Lykken, QJ Li - Immunologic Research, 2011 - Springer
CD4 T cells are an integral part of adaptive immunity. microRNAs have been identified as
fundamental regulators of post-transcriptional programs and to play roles in T lymphocytes' …

MicroRNAs are key regulators controlling iNKT and regulatory T-cell development and function

L Zhou, JJ Park, Q Zheng, Z Dong, Q Mi - Cellular & molecular …, 2011 - nature.com
MicroRNAs (miRNAs) are an abundant class of evolutionarily conserved, small, non-coding
RNAs that post-transcriptionally regulate expression of their target genes. Emerging …

MicroRNA regulation of molecular networks mapped by global microRNA, mRNA, and protein expression in activated T lymphocytes

YA Grigoryev, SM Kurian, T Hart… - The Journal of …, 2011 - journals.aai.org
MicroRNAs (miRNAs) regulate specific immune mechanisms, but their genome-wide
regulation of T lymphocyte activation is largely unknown. We performed a multidimensional …