Clinical utility of human papillomavirus genotyping in cervical cancer screening: a systematic review

JH Bonde, MT Sandri, DS Gary… - Journal of lower genital …, 2020 - journals.lww.com
Objective Thirteen human papillomavirus (HPV) genotypes are associated with the highest
risk of cervical disease/cancer; however, the risk of disease progression and cancer is …

[HTML][HTML] The Onclarity human papillomavirus trial: design, methods, and baseline results

MH Stoler, TC Wright Jr, V Parvu, L Vaughan… - Gynecologic …, 2018 - Elsevier
Objectives The baseline phase of the Onclarity trial was conducted to determine the
screening performance of the Onclarity human papillomavirus (HPV) assay for detecting …

Role of HPV genotype, multiple infections, and viral load on the risk of high-grade cervical neoplasia

R Adcock, J Cuzick, WC Hunt, RM McDonald… - … Biomarkers & Prevention, 2019 - AACR
Background: Human papillomavirus (HPV) testing provides a much more sensitive method
of detection for high-grade lesions than cytology, but specificity is low. Here, we explore the …

Diagnostic accuracy of human papillomavirus testing in primary cervical screening: a systematic review and meta-analysis of non-randomized studies

G Koliopoulos, M Arbyn, P Martin-Hirsch, M Kyrgiou… - Gynecologic …, 2007 - Elsevier
OBJECTIVE: This is a meta-analysis of studies comparing HPV testing to cytology with
regard to their accuracy in the detection of underlying high grade cervical intraepithelial …

Human papillomavirus types in 115,789 HPV‐positive women: a meta‐analysis from cervical infection to cancer

P Guan, R Howell‐Jones, N Li, L Bruni… - … journal of cancer, 2012 - Wiley Online Library
Genotyping may improve risk stratification of high‐risk (HR) human papillomavirus (HPV)‐
positive women in cervical screening programs; however, prospective data comparing the …

Human papillomavirus testing versus cytology in primary cervical cancer screening: End‐of‐study and extended follow‐up results from the Canadian cervical cancer …

SD Isidean, MH Mayrand… - … journal of cancer, 2016 - Wiley Online Library
The Canadian Cervical Cancer Screening Trial was a randomized controlled trial comparing
the performance of human papillomavirus (HPV) testing and Papanicolaou cytology to …

Real-world data on cervical cancer risk stratification by cytology and HPV genotype to inform the management of HPV-positive women in routine cervical screening

D Hashim, B Engesæter, G Baadstrand Skare… - British Journal of …, 2020 - nature.com
Background HPV16/18 detection may improve cervical cancer risk stratification and better
guide which HPV-positive women warrant immediate colposcopy/biopsy. We estimated risks …

[HTML][HTML] Prevalence of high-risk human papilloma virus genotypes and associated risk of cervical precancerous lesions in a large US screening population: data from …

J Monsonego, JT Cox, C Behrens, M Sandri… - Gynecologic …, 2015 - Elsevier
Objective We assessed the age-related prevalence of high risk human papillomavirus (HR-
HPV) genotypes and the genotype-associated risk for high-grade cervical intraepithelial …

[HTML][HTML] Stratified risk of high-grade cervical disease using onclarity HPV extended genotyping in women,≥ 25 years of age, with NILM cytology

MH Stoler, TC Wright Jr, V Parvu, K Yanson… - Gynecologic …, 2019 - Elsevier
Objectives Increasing evidence suggests that extended human papillomavirus (HPV)
genotyping (beyond 16/18) is effective for risk stratification in women with normal cytology …

Human papillomavirus in cervical cancer screening: important role as biomarker

GAV Boulet, CAJ Horvath, S Berghmans… - … Biomarkers & Prevention, 2008 - AACR
Cervical cytology screening has reduced cervical cancer morbidity and mortality but shows
important shortcomings in terms of sensitivity and specificity. Infection with distinct types of …