Obesity, leptin and breast cancer: epidemiological evidence and proposed mechanisms
S Andò, L Gelsomino, S Panza, C Giordano… - Cancers, 2019 - mdpi.com
The prevalence of obesity has been steadily increasing over the past few decades in several
developed and developing countries, with resultant hazardous health implications …
developed and developing countries, with resultant hazardous health implications …
Obesity and breast cancer: role of leptin
F Sánchez-Jiménez, A Pérez-Pérez… - Frontiers in …, 2019 - frontiersin.org
Obesity-related breast cancer is an important threat that affects especially post-menopausal
women. The link between obesity and breast cancer seems to be relying on the …
women. The link between obesity and breast cancer seems to be relying on the …
Obesity and breast cancer: status of leptin and adiponectin in pathological processes
ME Grossmann, A Ray, KJ Nkhata… - Cancer and Metastasis …, 2010 - Springer
It is well recognized that obesity increases the risk of various cancers, including breast
malignancies in postmenopausal women. Furthermore, obesity may adversely affect tumor …
malignancies in postmenopausal women. Furthermore, obesity may adversely affect tumor …
Circulating levels of leptin, adiposity and breast cancer risk
MH Wu, YC Chou, WY Chou, GC Hsu, CH Chu… - British journal of …, 2009 - nature.com
The present case–control study was to investigate the relationships of plasma leptin level
and anthropometric measures of adiposity with the risk of breast cancer. Questionnaire …
and anthropometric measures of adiposity with the risk of breast cancer. Questionnaire …
Linkage between obesity leptin and breast cancer
MF Atoum, F Alzoughool… - Breast Cancer: Basic …, 2020 - journals.sagepub.com
Many cancers might be influenced by obesity, including breast cancer, the leading cause of
cancer death among women. Obesity is a complex state associated with multiple …
cancer death among women. Obesity is a complex state associated with multiple …
Adverse effects of obesity on breast cancer prognosis, and the biological actions of leptin
DP Rose, EM Gilhooly… - … journal of oncology, 2002 - spandidos-publications.com
Leptin is a hormone with multiple biological actions which is produced predominantly by
adipose tissue; in humans, plasma levels correlate with total body fat, and particularly high …
adipose tissue; in humans, plasma levels correlate with total body fat, and particularly high …
The integrative role of leptin, oestrogen and the insulin family in obesity‐associated breast cancer: potential effects of exercise
S Schmidt, JM Monk, LE Robinson… - Obesity …, 2015 - Wiley Online Library
Obesity is an established risk factor for postmenopausal breast cancer. The mechanisms
through which obesity influences the development and progression of breast cancer are not …
through which obesity influences the development and progression of breast cancer are not …
The weight of obesity in breast cancer progression and metastasis: Clinical and molecular perspectives
The escalating epidemic of overweight and obesity is currently recognized as one of the
most significant health and economic concern worldwide. At the present time, over 1.9 billion …
most significant health and economic concern worldwide. At the present time, over 1.9 billion …
Obesity hormone leptin: a new target in breast cancer?
E Surmacz - Breast Cancer Research, 2007 - Springer
Leptin is a multifunctional hormone produced mainly by the adipose tissue and involved in
the regulation of food intake and energy balance. In addition, leptin can stimulate mitogenic …
the regulation of food intake and energy balance. In addition, leptin can stimulate mitogenic …
Leptin, obesity and breast cancer: progress to understanding the molecular connections
Highlights•Obesity is a pandemic condition associated with both risk and prognosis of breast
cancer.•The adipokine leptin is a plausible molecular link between obesity and breast …
cancer.•The adipokine leptin is a plausible molecular link between obesity and breast …