Advances in platelet function testing—light transmission aggregometry and beyond
J Le Blanc, F Mullier, C Vayne… - Journal of clinical …, 2020 - mdpi.com
Platelet function testing is essential for the diagnosis of hemostasis disorders. While there
are many methods used to test platelet function for research purposes, standardization is …
are many methods used to test platelet function for research purposes, standardization is …
[HTML][HTML] Platelet preparation for function testing in the laboratory and clinic: Historical and practical aspects
B Hechler, A Dupuis, PH Mangin, C Gachet - Research and practice in …, 2019 - Elsevier
Laboratory tests of platelet function are instrumental in studying platelet physiology and
inherited or acquired platelet abnormalities. Light transmission aggregometry, developed in …
inherited or acquired platelet abnormalities. Light transmission aggregometry, developed in …
Laboratory testing for platelet function disorders
SJ Israels - International Journal of Laboratory Hematology, 2015 - Wiley Online Library
Platelet function testing is both complex and labor intensive. A stepwise approach to the
evaluation of patients with suspected platelet disorders will optimize the use of laboratory …
evaluation of patients with suspected platelet disorders will optimize the use of laboratory …
Light transmission aggregometry
JP Frontroth - Haemostasis: methods and protocols, 2013 - Springer
Laboratory testing of platelet function is essential for the diagnosis of several congenital and
acquired platelet disorders. Moreover, it is increasingly being utilized to monitor the efficacy …
acquired platelet disorders. Moreover, it is increasingly being utilized to monitor the efficacy …
[PDF][PDF] Results of a worldwide survey on the assessment of platelet function by light transmission aggregometry: a report from the platelet physiology subcommittee of …
Background: Light transmission aggregometry (LTA) is the most common method used in
clinical and research laboratories to assess platelet function. However, the method has …
clinical and research laboratories to assess platelet function. However, the method has …
[HTML][HTML] Validation of flow cytometric analysis of platelet function in patients with a suspected platelet function defect
I Van Asten, REG Schutgens, M Baaij… - Journal of Thrombosis …, 2018 - Elsevier
Essentials• The diagnosis of mild platelet function disorders (PFDs) is challenging.•
Validation of flow cytometric testing in patients with suspected PFDs is required.• Flow …
Validation of flow cytometric testing in patients with suspected PFDs is required.• Flow …
The level of laboratory testing required for diagnosis or exclusion of a platelet function disorder using platelet aggregation and secretion assays
The major advances from research on platelet molecular and cell biology, physiology, and
pathophysiology over the past decades have not been adequately translated to clinical …
pathophysiology over the past decades have not been adequately translated to clinical …
Platelet function analysis
P Harrison - Blood reviews, 2005 - Elsevier
Since the last guidelines for BCSH platelet function testing were written in the late 1980s,
many new tests have become available. Previously most platelet function tests were …
many new tests have become available. Previously most platelet function tests were …
Platelet function testing: update and future directions
JB Larsen, AM Hvas, JA Hojbjerg - Seminars in Thrombosis …, 2023 - thieme-connect.com
Platelets play a key role in maintaining normal hemostasis and are also recognized as
partners in the development of arterial thrombosis. Today, platelet function testing is used for …
partners in the development of arterial thrombosis. Today, platelet function testing is used for …
Centrifugation speed affects light transmission aggregometry
M Merolla, MA Nardi, JS Berger - International journal of …, 2012 - Wiley Online Library
Background: Light transmission aggregometry (LTA) is considered the gold standard for
investigating platelet activity ex vivo. However, LTA protocols are not standardized, and …
investigating platelet activity ex vivo. However, LTA protocols are not standardized, and …
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