Integration of sensory input and computation of behavioural output is a dynamic process
involving diverse populations of cells often distributed throughout the brain. To study this …

Optogenetics has revolutionized the toolbox arsenal that neuroscientists now possess to
investigate neuronal circuit function in intact and living animals. With a combination of light …

Optogenetic tools can be used to manipulate neuronal activity in a reversible and specific
manner. In recent years, such methods have been applied to uncover causal relationships …

Zebrafish became a model of choice for neurobiology because of the transparency of its
brain and because of its amenability to genetic manipulation. In particular, at early stages of …

The zebrafish larva, Danio rerio, provides superb genetic access for studying how
systematic variations in behavioral profiles relate to differences in brain activity. Larvae …

We introduce an all-optical technique that enables volumetric imaging of brain-wide calcium
activity and targeted optogenetic stimulation of specific brain regions in unrestrained larval …

The brain consists of neural circuits that are assemblies of various neuron types. For
understanding how the brain works, it is essential to identify the functions of each type of …

Optogenetic actuators with diverse spectral tuning, ion selectivity and kinetics are constantly
being engineered providing powerful tools for controlling neural activity with subcellular …

A fundamental problem in neuroscience is to understand the causal relationship between
neuronal activity in the brain and behaviour of the animal. To effectively test how neural …

Optogenetic actuators with diverse spectral tuning, ion selectivity and kinetics are constantly
being engineered providing powerful tools for controlling neural activity with subcellular …