Skeletal muscle degenerative diseases and strategies for therapeutic muscle repair

M Tabebordbar, ET Wang… - Annual Review of …, 2013 - annualreviews.org
Skeletal muscle is a highly specialized, postmitotic tissue that must withstand chronic
mechanical and physiological stress throughout life to maintain proper contractile function …

Mechanisms of skeletal muscle repair and regeneration in health and disease

DE Michele - The FEBS Journal, 2022 - Wiley Online Library
Skeletal muscle is a structurally and functionally remarkable tissue composed of
multinucleated post‐mitotic muscle fibres. These fibres are filled with an exquisite, near …

Muscle injuries and repair: what's new on the horizon!

J Huard, A Lu, X Mu, P Guo, Y Li - Cells Tissues Organs, 2016 - karger.com
Although we recognize the many advantages of improved musculoskeletal health, we also
note that our ability to sustain this health and to maintain quality of life in an aging population …

Muscle wasting diseases: novel targets and treatments

R Furrer, C Handschin - Annual review of pharmacology and …, 2019 - annualreviews.org
Adequate skeletal muscle plasticity is an essential element for our well-being, and
compromised muscle function can drastically affect quality of life, morbidity, and mortality …

Current methods for skeletal muscle tissue repair and regeneration

J Liu, D Saul, KO Böker, J Ernst… - BioMed research …, 2018 - Wiley Online Library
Skeletal muscle has the capacity of regeneration after injury. However, for large volumes of
muscle loss, this regeneration needs interventional support. Consequently, muscle injury …

Regeneration versus fibrosis in skeletal muscle

AL Moyer, KR Wagner - Current opinion in rheumatology, 2011 - journals.lww.com
Regeneration versus fibrosis in skeletal muscle : Current Opinion in Rheumatology
Regeneration versus fibrosis in skeletal muscle : Current Opinion in Rheumatology Log in or …

Shared and distinct mechanisms of skeletal muscle atrophy: a narrative review

D Wilburn, A Ismaeel, S Machek, E Fletcher… - Ageing research …, 2021 - Elsevier
Maintenance of skeletal muscle mass and function is an incredibly nuanced balance of
anabolism and catabolism that can become distorted within different pathological conditions …

Muscle injury and repair

Y Li, J Cummins, J Huard - Current opinion in orthopaedics, 2001 - journals.lww.com
Muscle injury presents a challenging problem in traumatology and is frequently encountered
in sports medicine. The injury can occur via a variety of mechanisms, ranging from direct …

Emerging new tools to study and treat muscle pathologies: genetics and molecular mechanisms underlying skeletal muscle development, regeneration, and disease

C Crist - The Journal of Pathology, 2017 - Wiley Online Library
Skeletal muscle is the most abundant tissue in our body, is responsible for generating the
force required for movement, and is also an important thermogenic organ. Skeletal muscle is …

Prospect for pharmacological therapies to treat skeletal muscle dysfunction

MN Meriggioli, R Roubenoff - Calcified tissue international, 2015 - Springer
Skeletal muscle weakness is a leading cause of mobility disability in the elderly
(sarcopenia), as a complication of acute or chronic illness (cachexia), and due to inherited or …