Pathological fear, anxiety and negative affect exhibit distinct neurostructural signatures: evidence from psychiatric neuroimaging meta-analysis

X Liu, B Klugah-Brown, R Zhang, H Chen… - Translational …, 2022 - nature.com
Internalizing disorders encompass anxiety, fear and depressive disorders, which exhibit
overlap at both conceptual and symptom levels. Given that a neurobiological evaluation is …

Gray matter abnormalities in patients with major depressive disorder and social anxiety disorder: a voxel-based meta-analysis

J Liang, Q Yu, Y Liu, Y Qiu, R Tang, L Yan… - Brain Imaging and …, 2023 - Springer
Background Major depressive and social anxiety disorders have a high comorbidity rate and
similar cognitive patterns. However, their unique and shared neuroanatomical …

Neural circuits in anxiety and stress disorders: a focused review

ER Duval, A Javanbakht, I Liberzon - Therapeutics and clinical risk …, 2015 - Taylor & Francis
Anxiety and stress disorders are among the most prevalent neuropsychiatric disorders. In
recent years, multiple studies have examined brain regions and networks involved in anxiety …

Distinct grey matter volume alterations in adult patients with panic disorder and social anxiety disorder: A systematic review and voxel-based morphometry meta …

X Wang, B Cheng, S Wang, F Lu, Y Luo, X Long… - Journal of Affective …, 2021 - Elsevier
Background The paradox of similar diagnostic criteria but potentially different
neuropathologies in panic disorder (PD) and social anxiety disorder (SAD) needs to be …

The common traits of the ACC and PFC in anxiety disorders in the DSM-5: meta-analysis of voxel-based morphometry studies

J Shang, Y Fu, Z Ren, T Zhang, M Du, Q Gong, S Lui… - PloS one, 2014 - journals.plos.org
Background The core domains of social anxiety disorder (SAD), generalized anxiety
disorder (GAD), panic disorder (PD) with and without agoraphobia (GA), and specific phobia …

Personalized brain circuit scores identify clinically distinct biotypes in depression and anxiety

L Tozzi, X Zhang, A Pines, AM Olmsted, ES Zhai… - Nature Medicine, 2024 - nature.com
There is an urgent need to derive quantitative measures based on coherent neurobiological
dysfunctions or 'biotypes' to enable stratification of patients with depression and anxiety. We …

Developing a clinical translational neuroscience taxonomy for anxiety and mood disorder: protocol for the baseline-follow up Research domain criteria Anxiety and …

LM Williams, AN Goldstein-Piekarski, N Chowdhry… - BMC psychiatry, 2016 - Springer
Background Understanding how brain circuit dysfunctions relate to specific symptoms offers
promise for developing a brain-based taxonomy for classifying psychopathology, identifying …

Common and different neural markers in major depression and anxiety disorders: A pilot structural magnetic resonance imaging study

E Maggioni, G Delvecchio, M Grottaroli… - Psychiatry Research …, 2019 - Elsevier
Although anxiety and depression often co-occur and share some clinical features, it is still
unclear if they are neurobiologically distinct or similar processes. In this study, we explored …

Neurobiological signatures of anxiety and depression in resting-state functional magnetic resonance imaging

DJ Oathes, B Patenaude, AF Schatzberg, A Etkin - Biological psychiatry, 2015 - Elsevier
Background There is increasing interest in using neurobiological measures to inform
psychiatric nosology. It is unclear at the present time whether anxiety and depression are …

Identification of common neural circuit disruptions in emotional processing across psychiatric disorders

LM McTeague, BM Rosenberg… - American Journal of …, 2020 - Am Psychiatric Assoc
Objective: Disrupted emotional processing is a common feature of many psychiatric
disorders. The authors investigated functional disruptions in neural circuitry underlying …