Frailty and post-operative outcomes in older surgical patients: a systematic review

HS Lin, JN Watts, NM Peel, RE Hubbard - BMC geriatrics, 2016 - Springer
Background As the population ages, increasing numbers of older adults are undergoing
surgery. Frailty is prevalent in older adults and may be a better predictor of post-operative …

Systematic review and meta-analysis of the association between frailty and outcome in surgical patients

K Oakland, R Nadler, L Cresswell… - The Annals of The …, 2016 - publishing.rcseng.ac.uk
Introduction Frailty is becoming increasingly prevalent in the elderly population although a
lack of consensus regarding a clinical definition hampers comparison of clinical studies …

Preoperative frailty evaluation: a promising risk-stratification tool in older adults undergoing general surgery

FC Ko - Clinical therapeutics, 2019 - Elsevier
Purpose General surgical procedures are among the most commonly performed operations
in the United States. Despite advances in surgical and anesthetic techniques and …

Impact of frailty on outcomes in surgical patients: a systematic review and meta-analysis

AC Panayi, AR Orkaby, D Sakthivel, Y Endo… - The American Journal of …, 2019 - Elsevier
Importance Age has historically been used to predict negative post-surgical outcomes. The
concept of frailty was introduced to explain the discrepancies that exist between patients' …

Effects of the frailty phenotype on post-operative complications in older surgical patients: a systematic review and meta-analysis

B Han, Q Li, X Chen - BMC geriatrics, 2019 - Springer
Background Frailty has been generally been associated with adverse events in older
patients under surgery. Frailty phenotype is the most widely used instrument in the research …

The prevalence of frailty and its association with clinical outcomes in general surgery: a systematic review and meta-analysis

J Hewitt, S Long, B Carter, S Bach, K McCarthy… - Age and …, 2018 - academic.oup.com
Objectives to investigate the prevalence and impact of frailty for general surgical patients.
Research design and methods we conducted a systematic review and meta-analysis …

Impact of frailty on outcomes after discharge in older surgical patients: a prospective cohort study

Y Li, JL Pederson, TA Churchill, AS Wagg… - Cmaj, 2018 - Can Med Assoc
BACKGROUND: Frailty is a state of vulnerability to diverse stressors. We assessed the
impact of frailty on outcomes after discharge in older surgical patients. METHODS: We …

Frailty as a predictor of surgical outcomes in older patients

MA Makary, DL Segev, PJ Pronovost, D Syin… - Journal of the American …, 2010 - Elsevier
BACKGROUND: Preoperative risk assessment is important yet inexact in older patients
because physiologic reserves are difficult to measure. Frailty is thought to estimate …

Systematic review and meta-analysis of frailty as a predictor of morbidity and mortality after major abdominal surgery

M Sandini, E Pinotti, I Persico, D Picone, G Bellelli… - BJS open, 2017 - academic.oup.com
Background Frailty is associated with poor prognosis, but the multitude of definitions and
scales of assessment makes the impact on outcomes difficult to assess. The aim of this study …

Routine frailty assessment predicts postoperative complications in elderly patients across surgical disciplines–a retrospective observational study

O Birkelbach, R Mörgeli, C Spies, M Olbert, B Weiss… - BMC …, 2019 - Springer
Background Frailty is a frequent and underdiagnosed functional syndrome involving
reduced physiological reserves and an increased vulnerability against stressors, with severe …