[HTML][HTML] Co-delivery of cyclopamine and doxorubicin mediated by bovine serum albumin nanoparticles reverses doxorubicin resistance in breast cancer by down …

Y Lu, Y Ma, C Feng, D Zhu, J Liu, L Chen… - Journal of …, 2019 - ncbi.nlm.nih.gov
Combination chemotherapy is considered to be one of the most effective treatments for
breast cancer by reducing the emergence of drug resistance. In this study, a novel drug …

Co-delivery of doxorubicin and RNA using pH-sensitive poly (β-amino ester) nanoparticles for reversal of multidrug resistance of breast cancer

S Tang, Q Yin, Z Zhang, W Gu, L Chen, H Yu, Y Huang… - Biomaterials, 2014 - Elsevier
An appropriate co-delivery system for chemotherapeutic agents and nucleic acid drugs will
provide a more efficacious approach for the treatment of breast cancer by reversing …

[HTML][HTML] Aptamer-functionalized hybrid nanoparticles to enhance the delivery of doxorubicin into breast cancer cells by silencing P-glycoprotein

S Chandra, HM Nguyen, K Wiltz, N Hall… - Journal of cancer …, 2020 - ncbi.nlm.nih.gov
Objective: The MDR of metastatic breast cancer cells is accompanied by the overexpression
of P-gp transporter. This study has been focused to determine whether silencing the …

Co-delivery of DOX and PDTC by pH-sensitive nanoparticles to overcome multidrug resistance in breast cancer

X Cheng, D Li, M Sun, L He, Y Zheng, X Wang… - Colloids and Surfaces B …, 2019 - Elsevier
Chemotherapeutic drugs have a series of limitations in the conventional clinical treatments,
mainly including serious adverse effects and multidrug resistance (MDR). Herein, we …

[HTML][HTML] Doxorubicin and resveratrol co-delivery nanoparticle to overcome doxorubicin resistance

Y Zhao, M Huan, M Liu, Y Cheng, Y Sun, H Cui, D Liu… - Scientific reports, 2016 - nature.com
With the extensive application of doxorubicin (DOX), DOX resistance has become one of the
main obstacles to the effective treatment of breast cancer. In this paper, DOX and resveratrol …

[HTML][HTML] A nuclear targeted Dox-aptamer loaded liposome delivery platform for the circumvention of drug resistance in breast cancer

X Li, X Wu, H Yang, L Li, Z Ye, Y Rao - Biomedicine & Pharmacotherapy, 2019 - Elsevier
The development of multidrug resistance (MDR) has become an increasingly serious
problem in cancer therapy. The cell membrane overexpression of P-glycoprotein (P-gp) …

Hyaluronic acid-coated poly (β-amino) ester nanoparticles as carrier of doxorubicin for overcoming drug resistance in breast cancer cells

T An, C Zhang, X Han, G Wan, D Wang, Z Yang… - RSC …, 2016 - pubs.rsc.org
Drug resistance is a major challenge for the clinical application of chemotherapeutic drugs.
In this study, a nanoparticle system containing hyaluronic acid (HA) shell and poly (β-amino) …

A self-assembled albumin based multiple drug delivery nanosystem to overcome multidrug resistance

B Chen, C Wu, RX Zhuo, SX Cheng - RSC Advances, 2015 - pubs.rsc.org
A facile strategy to construct a multiple drug delivery platform to overcome multidrug
resistance (MDR) was developed. A nano-sized albumin based drug delivery system with …

[HTML][HTML] Quercetin and doxorubicin co-encapsulated biotin receptor-targeting nanoparticles for minimizing drug resistance in breast cancer

L Lv, C Liu, C Chen, X Yu, G Chen, Y Shi, F Qin, J Ou… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The combination of a chemotherapeutic drug with a chemosensitizer has emerged as a
promising strategy for cancers showing multidrug resistance (MDR). Herein we describe the …

Enhanced antitumor effect of doxorubicin through active-targeted nanoparticles in doxorubicin-resistant triple-negative breast cancer

CH Hsiao, HL Huang, YH Chen, ML Chen… - Journal of Drug Delivery …, 2022 - Elsevier
Breast cancer is the most common cancer in women worldwide, and the incidence and
mortality rates have been increasing. Chemotherapy remains the main treatment strategy for …